Urinary sCD25 as a biomarker of lupus nephritis disease activity / (Record no. 81297)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03007cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032750.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210615s2021 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.M.Sc.2021.Ma.U |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mansour Gomaa Mohammed Saleh |
| 245 10 - TITLE STATEMENT | |
| Title | Urinary sCD25 as a biomarker of lupus nephritis disease activity / |
| Statement of responsibility, etc. | Mansour Gomaa Mohammed Saleh ; Supervised Heba Taher Othman , Hanan Ali Madani , Ahmed Salah Elden Sayed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | فى البول كمؤشر معملى لالتهاب الكلى فى مرضى الذئبه الحمراء sCD25استخدام |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mansour Gomaa Mohammed Saleh , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 152 P . : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Introduction: More than 60% of children with systemic lupus erythematosus (SLE) develop lupus nephritis (LN). T cells play an important role in the pathogenesis of lupus nephritis (LN). The role of IL-2 in autoimmune and inflammatory diseases is known clear and can be studied from different points of view including diagnosis and treatment of these diseases. Soluble IL-2 receptor (sCD25) is released by activated lymphocytes and may be a measure of lymphocyte activation. Aim: To evaluate the role of urinary soluble CD25 (sCD25) as a noninvasive biomarker of lupus nephritis (LN) in pediatric SLE patients in a cross-sectional study.Methods: Urinary levels of soluble CD25 (sCD25) were assessed in 60 children with SLE (20 with active lupus nephritis ,20 with nonactive lupus nephritis and 20 SLE patients had never nephritis) and compared to 40 age and sex matched healthy controls. Results: Levels of urinary soluble CD25 (sCD25) were significantly higher in patients with active lupus nephritis (±45.8 ng/ml) than those inactive lupus nephritis (±29.4 ng/ml) (P<0.002). Also, levels of urinary soluble CD25 (sCD25) were higher in patients with inactive lupus nephritis (±29.4 ng/ml) than those without lupus nephritis (±16.2 ng/ml) (P<0.001) . Children with SLE had elevated urinary soluble CD25 (sCD25) (±16.2 ng/ml) as compared to controls (±9.9 ng/ml) (P<0.001). In our studied groups, urinary levels of soluble CD25 (sCD25) were correlated with increased serum creatinine and the quantitative and qualitative measures of proteinuria (P<0.001). Urinary of soluble CD25 (sCD25) was not significantly correlated with the complement levels and SLEDAI |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Active lupus nephritis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | juvenile SLE |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Urinary soluble CD25 (sCD25) |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Salah Elden Sayed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanan Ali Madani , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Taher Othman , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.M.Sc.2021.Ma.U | 01010110083645000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.M.Sc.2021.Ma.U | 01020110083645000 | 22.09.2023 | CD - Rom | 83645.CD |