Utilization of a nanocarrier as a feasible tool for liver targeting of a certain drug / (Record no. 81357)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02065cam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210622s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.Ph.D.2021.Sh.U |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shaimaa Ali Ali Radwan Moustafa |
| 245 10 - TITLE STATEMENT | |
| Title | Utilization of a nanocarrier as a feasible tool for liver targeting of a certain drug / |
| Statement of responsibility, etc. | Shaimaa Ali Ali Radwan Moustafa ; Supervised Raguia Aly Shoukri , Aliaa Nabil Elmeshad |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | استخدام الحاملات متناهية الصغر كوسيلة ملائمة لتوصيل عقار معين إلى الكبد |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Shaimaa Ali Ali Radwan Moustafa , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 188 P . : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Gallic acid (GA) is characterized by its protective properties towards induced apoptosis in tumor cells, carbon tetrachloride induced liver injury and lung fibroblasts. It has the ability to hinder the proliferation of activated hepatic stellate cells (aHSCs) and control progression of liver fibrosis. However, the hydrophilic properties of GA hindered its entrapment in different vesicles formulations due to its fast partitioning with the surrounding aqueous media. Moreover, GA is poorly absorbed and rapidly metabolized leading to faster elimination and shorter peak plasma concentration and hence, diminished bioavailability. The present study aims to encapsulate GA into different nanocarrier systems for the passive and active targeting of GA to aHSCs for the effective treatment of liver fibrosis |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Activated hepatic stellate cells (aHSCs) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Gallic acid (GA) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Liver fibrosis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aliaa Nabil Elmeshad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Raguia Aly Shoukri , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.Ph.D.2021.Sh.U | 01010110083698000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.Ph.D.2021.Sh.U | 01020110083698000 | 22.09.2023 | CD - Rom | 83698.CD |