Immunohistochemical expression of fak and pcna in odontogenic keratocyst, orthokeratinized odontogenic cyst, dentigerous cyst and glandular odontogenic cyst : (Record no. 81406)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03309cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032753.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210627s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.09.14.Ph.D.2020.Se.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Seham Hazem Mohammed Elayouti |
| 245 10 - TITLE STATEMENT | |
| Title | Immunohistochemical expression of fak and pcna in odontogenic keratocyst, orthokeratinized odontogenic cyst, dentigerous cyst and glandular odontogenic cyst : |
| Remainder of title | In vitro study / |
| Statement of responsibility, etc. | Seham Hazem Mohammed Elayouti ; Supervised Heba Mahmoud Dahmoush , Hatem Wael Amer |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | فى الكيس الكرايتينى السنى وكيس الكيراتين المصطف والكيس المسنن والكيس الغدى السنى PCN و FAC التعبير المناعى الهيستوكيميائى : |
| Remainder of title | دراسه فى المختبر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Seham Hazem Mohammed Elayouti , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 94 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Odontogenic cysts are distinctive disorders that affect oral and maxillofacial tissues. The majority of odontogenic cysts such as dentigerous cysts (DCs) and orthokeratinized odontogenic cyst (OOCs) show an indolent course, whilst others demonstrate an aggressive behavior and may have higher recurrence rate like odontogenic keratocysts (OKCs) and glandular odontogenic cysts (GOCs). Aim: This study aimed to compare FAK and PCNA expression in OKC, OOC, DC and GOC and to attempt to correlate the findings to their variable clinical behaviors. Moreover, this study aimed to clarify the role of EMT in invasion potential, proliferation and aggressiveness of these lesions, thus helping to predict their prognosis, reaching the best treatment modality for the patients and lowering the recurrence rates. Methodology: Double Immunostaining technique for FAK and PCNA was performed on the same tissue specimens using two types of chromogens (DAB and AEC). DAB chromogen was used for the assessment of nuclear expression of PCNA, while AEC chromogen was used for the assessment of cytoplasmic expression of FAK. Results: The greatest mean of the nuclear immunoexpression of PCNA was recorded in GOC group, followed by the OKC and OOC groups, whereas the lowest value was the DC group, while the greatest mean area percent of the cytoplasmic expression of FAK was recorded in OKC group, followed by the GOC and OOC groups, whereas the lowest value was recorded in DC group. Conclusions: OKC has the highest EMT ability followed by GOC, while GOC has the highest proliferation activity followed by OKC. On the other hand, OOC and DC have the lowest EMT ability and proliferation activity, which can explain the diverse behavior of those odontogenic cysts |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Odontogenic cysts |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Odontogenic keratocysts (OKCs) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PCNA |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hatem Wael Amer , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Mahmoud Dahmoush , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.09.14.Ph.D.2020.Se.I | 01010110083763000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.09.14.Ph.D.2020.Se.I | 01020110083763000 | 22.09.2023 | CD - Rom | 83763.CD |