Assessment of mercury, lead and cadmium as environmental risk factors in a sample of multiple sclerosis patients presented to Kasr Alainy Hospital / (Record no. 81823)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03293cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032805.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210823s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.13.Ph.D.2021.Sa.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Samar Ramadan Mohamed Abdelghani |
| 245 10 - TITLE STATEMENT | |
| Title | Assessment of mercury, lead and cadmium as environmental risk factors in a sample of multiple sclerosis patients presented to Kasr Alainy Hospital / |
| Statement of responsibility, etc. | Samar Ramadan Mohamed Abdelghani ; Supervised Usama Mohamed Elbarrany , Tarek Mohamed Yehia Omar , Ahmed Abdelmoneam Elshatory |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم الزئبق والرصاص والكادميوم كعوامل خطر بيئية فى عينة من مرضى التصلب المتعدد المترددين على مستشفى قصر العينى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Samar Ramadan Mohamed Abdelghani , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 121 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Forensic Medicine and Clinical Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: multiple sclerosis (ms) is a demyelinating inflammatory disease of the central nervous system (cns) white matter. environmental and genetic factors have been implicated in its pathogenesis. heavy metals generate free radicals causing alteration in genetic material and blood brain barrier (bbb) damage. in addition, intracellular accumulation of certain heavy metals can trigger autoimmune reaction against myelin proteins and nerves cytoskeletal proteins subjects & methods: the present study was carried out in the period between september 2019 and may 2021. 86 ms patients and 86 healthy controls were included. whole blood levels of mercury (hg), cadmium (cd) and lead (pb) in microgram/liter (og/l) in addition to zinc (zn) and copper (cu) in milligram/liter (mg/l) were measured. the current study also discussed heavy metals exposure risks between the two studied groups as well as physiological-toxic metals interactions. results: the current work demonstrated significantly higher levels of pb, cd and hg and significantly lower levels of zn and cu as well as cu/zn in ms patients than controls. heavy metals exposure risks were significantly higher in ms patients than controls regarding frequent use of cosmetics/ sanitary products and tap water consumption in addition to environmental, occupational and medical exposure. lower cu and zn levels were accompanied by higher levels of pb, hg and cd. however, these negative correlations were only significant between cu and both of hg and pb. conclusion: the current work demonstrated significant relation between toxic metals levels and ms. in addition, a complex profile of altered elements rather than a single element imbalance in ms pathogenesis is suggested |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cadmium |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Heavy metals |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Lead |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Abdelmoneam Elshatory , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tarek Mohamed Yehia Omar , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Usama Mohamed Elbarrany , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.13.Ph.D.2021.Sa.A | 01010110083993000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.13.Ph.D.2021.Sa.A | 01020110083993000 | 22.09.2023 | CD - Rom | 83993.CD |