Assessment of ENHO gene polymorphism in psoriasis vulgaris and its relation to Metabolic Syndrome parameters / (Record no. 82101)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03135cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032814.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210913s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.M.Sc.2021.Ma.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mai Ramzi Helmi Alfarra |
| 245 10 - TITLE STATEMENT | |
| Title | Assessment of ENHO gene polymorphism in psoriasis vulgaris and its relation to Metabolic Syndrome parameters / |
| Statement of responsibility, etc. | Mai Ramzi Helmi Alfarra ; Supervised Dina Mohammed Kadry Ismail , Mona Mohamed Ibrahim Elkalioby , Olfat Gamil Shaker |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | لدى مريض الصدفية وتحديد علاقته بمتلازمة التمثيل الغذائى ENHO تقييم تعدد الشكل الجنينى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mai Ramzi Helmi Alfarra , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 182 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: Evaluation of ENHO gene polymorphism (rs2281997, rs72735260) and serum adropin levels in patients with psoriasis and determining their relation to metabolic syndrome. Patients And Methods: The study included 150 patients with psoriasis vulgaris and 150 matched controls. Each group was further divided according to presence/absence of metabolic syndrome into two subgroups. Detailed history, body surface area (BSA), PASI score, dermatology life quality index (DLQI) were recorded for all patients. Metabolic parameters were tested for both patients and controls. ENHO gene polymorphism (rs2281997 and rs72735260) were detected by Taqman technique for all patients and controls. Adropin level was assessed for 40 psoriasis patients and 40 controls using ELISA.Results: TT genotype and T allele variant of rs2281997 (C/T) gene were associated with psoriasis (p<0.001* and p=0.004* respectively) .TT genotype and T allele variant of rs2281997 (C/T) gene were also associated with increased systolic (p= 0.011* and 0.001* respectively) and diastolic blood pressure (p= 0.018* and 0.004* respectively). C allele of rs2281997 was statistically more frequently associated with scalp type of psoriasis (P=0.006*).There was no difference in the prevalence of rs72735260 (G/T) genotypes (p=0.493) and allele variants (p =0.522) between psoriasis patients and controls. However, GT genotype of rs72735260 (G/T) gene was associated with elevated serum cholesterol (p= 0.046*). GT genotype and T allele of rs72735260 (G/T) gene were associated with earlier age of onset of psoriasis (p= 0.023* and p=0.035* respectively) and with the type I psoriasis (P =0.028* and 0.018* respectively) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Metabolic Syndrome parameters |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polymorphism |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Psoriasis vulgaris |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dina Mohammed Kadry Ismail , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Mohamed Ibrahim Elkalioby , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olfat Gamil Shaker , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2021.Ma.A | 01010110084161000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2021.Ma.A | 01020110084161000 | 22.09.2023 | CD - Rom | 84161.CD |