Analytical studies of some drugs containing amide group and its mono-acyl derivative / (Record no. 82536)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02663cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211013s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.03.Ph.D.2021.Ay.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Aya Hosam Helmy |
| 245 10 - TITLE STATEMENT | |
| Title | Analytical studies of some drugs containing amide group and its mono-acyl derivative / |
| Statement of responsibility, etc. | Aya Hosam Helmy ; Supervised Badr A. Elzeiny , Soheir A. Ahmed , Nadia F. Youssef |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات تحليلية لبعض الادويه التى تحتوى على مجموعه الاميد ومشتقها احادى الاسيل |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Aya Hosam Helmy , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 163 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The health and the safety of pharmaceutical products consumers are protected by the national control laboratories. Prior the pharmaceutical product is approved to the market several tests must be applied to ensure that these products meet the accepted standard of quality, efficacy and safety. However, time consuming method is usually stood as barrier to achieve fast results. Moreover, developing country laboratories are suffering from deficiency of sophisticated analytical instruments. This study concerned with developing fast, simple, inexpensive and accurate accessible analytical methods using chromatographic and spectroscopic techniques for the simultaneous determination of selected drugs containing amide group like perampanel and carbamazepine or its mono-acyl derivative like aniracetam. Stability-indicating chromatographic methods were applied to determine aniracetam in presence of its degradation products using 25 cm, C18 column with limit of detection of 0.216 æg/ml for HPLC method, 0.009 æg/band for NP-TLC and 0.008 for RP-TLC methods. Comparative kinetics studies and pH rate-profile were applied to determine the rate and order of degradation reaction using the developed HPLC-UV method. Spectroflourimetric method was used to determine aniracetam by fluorescence quenching of tyrosine and L-tryptophan fluorescent amino acids with LOD 0.104æg/ml and 0.140æg/ml, respectively |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Aniracetam |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Perampanel |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Stability |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Badr A. Elzeiny , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nadia F. Youssef , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Soheir A. Ahmed , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.03.Ph.D.2021.Ay.A | 01010110084399000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.03.Ph.D.2021.Ay.A | 01020110084399000 | 22.09.2023 | CD - Rom | 84399.CD |