MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03102cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
211020s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.26.Ph.D.2021.Ge.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gehad Ahmed Basuony Yousef |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Study on the potential effects of experimental blastocystis infection on lactase enzyme activity, histopathological, inflammatory and apoptotic changes in intestines of mice / |
| Statement of responsibility, etc. |
Gehad Ahmed Basuony Yousef ; Supervised Maha Mohammed Abou Elmagd Basyoni , Eman Ali Mohamed Mostafa , Mohamed Abbas Shemis |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسة عن تاثير المحتمل لعدوى البلاستوسيستس التجريبيه على نشاط انزيم اللاكتيز والتغيرات المرضيه فى الانسجه ودلائل الالتهاب وموت الخلايا المبرمج فى امعاء الفئران |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Gehad Ahmed Basuony Yousef , |
| Date of publication, distribution, etc. |
2021 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
217 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Parasitology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The present study was carried out on 20 laboratory bred male mice in Theodore Bilharz Research Institute to evaluate the influence of Blastocystis infection on lactase enzyme activity in the brush border of the intestine in experimentally infected mice and to detect the possible pathological changes, inflammatory and apoptotic markers provoked by Blastocystis infection. Assessment of lactase enzyme activity by lactase assay colorimetric kit on intestinal tissue and spectrophotometric measurements showed significant reduction of lactase enzyme in Blastocystis infected groups (Group II 4.593 ± 0.775 and Group IV 2.484± 0.908 with p values < 0.001) compared to the non-infected groups ( Group I 8.780 ± 0.263 and Group III 13.883 ±6.388 with p values< 0.001).In addition, histopathological examination of small intestinal tissue sections of infected mice showed moderate active inflammation with moderate number of vacuolar forms of Blastocystis while histopathological examination of large intestinal tissue sections showed severe active colitis with large number of vacuolar forms of Blastocystis.Furthermore, Immunohistochemical staining with tumor necrosis factor alpha (TNF-Ü) detected a significant elevation in Blastocystis infected groups compared to non-infected groups. Also, there is a significant elevation of proapoptotic marker BAX protein in Blastocystis infected groups and significant reduction of antiapoptotic BCL-2 in Blastocystis infected groups compared to the non-infected groups |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Blastocystis |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Lactase |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Spectrophotometer |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Eman Ali Mohamed Mostafa , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Maha Mohammed Abou Elmagd Basyoni , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Abbas Shemis , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
