Efficacy of inactivated AI H5 vaccines in SPF chicks against challenge with Egyptian H5N8 clade 2.3.4.4b viruses isolated in 2017 and 2018 / (Record no. 82752)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03280cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032834.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211024s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.17.M.Sc.2021.Am.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amena Abdelmoeid Sayed Mohamed |
| 245 10 - TITLE STATEMENT | |
| Title | Efficacy of inactivated AI H5 vaccines in SPF chicks against challenge with Egyptian H5N8 clade 2.3.4.4b viruses isolated in 2017 and 2018 / |
| Statement of responsibility, etc. | Amena Abdelmoeid Sayed Mohamed ; Supervised Hussein Aly Hussein Ahmed , Ayman Hany Mahmoud Eldeeb , Mounir Mohamed Elsafty |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | المصرية المعزولة فى عامى2017 و 2018 b2.3.4.4 فرع H5N8 المثبطة فى الكتاكيت الخالية من المسببات المرضية ضد اختبار التحدى باستخدام فيروسى H5 فعالية لقاحات إنفلونزا الطيور |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Amena Abdelmoeid Sayed Mohamed , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 116 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Virology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Vaccination is the routinely used tool for control of highly pathogenic avian influenza (HPAI) H5N8subtype in Egypt. Inactivated avian influenza vaccines are the most frequently registered and commercially used against avian influenza (AI)infection in poultry farms. Both genetic and antigenic mismatching between the seed strain used invaccine and the recent circulating HPAI H5N8 viruses may affect the efficiency of commercial vaccines used in AIcontrol in Egypt.In this study, we evaluated inactivatedAI commercial vaccines (H5N1, H5N2 and H5N3) in challenge trials using specific pathogen free (SPF) chicks at 2 and 3 weeks post vaccination (WPV). Two Egyptian HPAI H5N8 viruses isolated in 2017 and 2018 clade 2.3.4.4bwere used. Survival percentages, antibody titers and the virus shedding titers as well as the histopathological changes in kidney and spleen were recorded.All studied vaccines revealed protection percentages between 70 to 100 % within 10 dayspost challenge. Haemagglutination inhibition (HI)results of sera samples showed antibody titers ranged from 0.6 to 5.4 log2 starting 1 week (PV) with the highest titers at 4thWPV. Vaccinated challenged SPF chicks showed remarkable virus shedding reduction with an average of 2 log10 compared to control birds. Various histopathological lesions with different scores were demonstrated. H5N1 and H5N3 AI vaccines were the most effective against the challenge HPAI H5N8 viruses. We recommend annual evaluation of the currently used vaccines using the most prevalent challenge H5N8 viruses isolated from field outbreaks in poultry farms based on the annual surveillance for AI in Egypt |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Avian influenza |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Clade 2.3.4.4b |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Highly pathogenic H5N8 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ayman Hany Mahmoud Eldeeb , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hussein Aly Hussein Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mounir Mohamed Elsafty , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.17.M.Sc.2021.Am.E | 01010110084511000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.17.M.Sc.2021.Am.E | 01020110084511000 | 22.09.2023 | CD - Rom | 84511.CD |