MARC details
000 -LEADER |
fixed length control field |
03267cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
211128s2021 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.28.M.Sc.2021.Ah.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Ahmed Mahmoud Ahmed Sayed |
245 10 - TITLE STATEMENT |
Title |
Serum erythropoietin level for detection of kidney and brain injuries in asphyxiated neonates in neonatal intensive care unit / |
Statement of responsibility, etc. |
Ahmed Mahmoud Ahmed Sayed ; Supervised Dina Mohamed Akmal , Yosra Aboelnaga Fahmy , Nermine Magdi Riad |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
مستوى الايرثروبيوتين فى الدم فى المبتسرين فى رعايه حديثي الولاده للتنبؤ باصابه الكلى والمخ بعد تعرضهم لنقص الأكسجين فى الولادة |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Ahmed Mahmoud Ahmed Sayed , |
Date of publication, distribution, etc. |
2021 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
109 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Background: Perinatal hypoxic-ischemic encephalopathy (HIE) is the leading cause of brain injury in the newborn and can result in long-term devastating consequences. Acute kidney injury (AKI) occurs in (50-72%) among asphyxiated term infants. Erythropoietin (EPO) is a hormone secreted by the kidney that stimulates the bone marrow for RBCs formation. The erythropoietin-producing kidney cells are sensitive to low oxygen levels in the blood that passes through the kidney.The aim of our study is to evaluate brain injury in full-term neonates with perinatal asphyxia by detecting specific biomarkers in the blood during fist days of life (erythropoietin). And evaluate kidney injury related to perinatal asphyxia. Materials and methods: A cross-sectional study included 80 full-term neonates in their first 96 hours of life: 40 healthy neonates, 14 newborns with clinical signs of mild HIE, 15 newborns with moderate HIE, 11 newborns of severe HIE. To study serum erythropoietin level for detection of kidney and brain injuries in asphyxiated neonates.Results: In our study we found that serum erythropoietin level was significantly higher in patients{u2019} group than control group. Serum erythropoietin level was significantly higher in severe cases of HIE than mild and moderate cases. In our study we found high serum creatinine level in patients group compared to controls group and this may reflect effect of hypoxia on kidney function. 50% of asphyxiated neonates were found to have AKI, and 95% were non-oliguric. In our study we found there was no significant difference between AKI group compared to non-AKI group as regard serum erythropoietin level. ROC curves were plotted for erythropoietin. Erythropoietin level greater than 10.5 mIU\ml showed a sensitivity of 67.5% and specificity of 82.5% and area under curve (AUC) of 70.0% |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Acute Kidney Injury |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Full-Term Neonates |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
HIE |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Dina Mohamed Akmal , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Nermine Magdi Riad , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Yosra Aboelnaga Fahmy , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |