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Serum erythropoietin level for detection of kidney and brain injuries in asphyxiated neonates in neonatal intensive care unit / (Record no. 83328)

MARC details
000 -LEADER
fixed length control field 03267cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 211128s2021 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.28.M.Sc.2021.Ah.S
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Ahmed Mahmoud Ahmed Sayed
245 10 - TITLE STATEMENT
Title Serum erythropoietin level for detection of kidney and brain injuries in asphyxiated neonates in neonatal intensive care unit /
Statement of responsibility, etc. Ahmed Mahmoud Ahmed Sayed ; Supervised Dina Mohamed Akmal , Yosra Aboelnaga Fahmy , Nermine Magdi Riad
246 15 - VARYING FORM OF TITLE
Title proper/short title مستوى الايرثروبيوتين فى الدم فى المبتسرين فى رعايه حديثي الولاده للتنبؤ باصابه الكلى والمخ بعد تعرضهم لنقص الأكسجين فى الولادة
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Ahmed Mahmoud Ahmed Sayed ,
Date of publication, distribution, etc. 2021
300 ## - PHYSICAL DESCRIPTION
Extent 109 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 ## - SUMMARY, ETC.
Summary, etc. Background: Perinatal hypoxic-ischemic encephalopathy (HIE) is the leading cause of brain injury in the newborn and can result in long-term devastating consequences. Acute kidney injury (AKI) occurs in (50-72%) among asphyxiated term infants. Erythropoietin (EPO) is a hormone secreted by the kidney that stimulates the bone marrow for RBCs formation. The erythropoietin-producing kidney cells are sensitive to low oxygen levels in the blood that passes through the kidney.The aim of our study is to evaluate brain injury in full-term neonates with perinatal asphyxia by detecting specific biomarkers in the blood during fist days of life (erythropoietin). And evaluate kidney injury related to perinatal asphyxia. Materials and methods: A cross-sectional study included 80 full-term neonates in their first 96 hours of life: 40 healthy neonates, 14 newborns with clinical signs of mild HIE, 15 newborns with moderate HIE, 11 newborns of severe HIE. To study serum erythropoietin level for detection of kidney and brain injuries in asphyxiated neonates.Results: In our study we found that serum erythropoietin level was significantly higher in patients{u2019} group than control group. Serum erythropoietin level was significantly higher in severe cases of HIE than mild and moderate cases. In our study we found high serum creatinine level in patients group compared to controls group and this may reflect effect of hypoxia on kidney function. 50% of asphyxiated neonates were found to have AKI, and 95% were non-oliguric. In our study we found there was no significant difference between AKI group compared to non-AKI group as regard serum erythropoietin level. ROC curves were plotted for erythropoietin. Erythropoietin level greater than 10.5 mIU\ml showed a sensitivity of 67.5% and specificity of 82.5% and area under curve (AUC) of 70.0%
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Acute Kidney Injury
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Full-Term Neonates
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term HIE
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Dina Mohamed Akmal ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Nermine Magdi Riad ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Yosra Aboelnaga Fahmy ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.28.M.Sc.2021.Ah.S 01010110084856000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.28.M.Sc.2021.Ah.S 01020110084856000 22.09.2023 CD - Rom 84856.CD