Evaluation of clinical out-comes in pediatric patients with intrahepatic cholestasis after partial external biliary diversion / (Record no. 83352)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03449cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032854.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211129s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.Ph.D.2021.Ha.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hadeer Mohamed Nasr Eldin Ibrahim Azab |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of clinical out-comes in pediatric patients with intrahepatic cholestasis after partial external biliary diversion / |
| Statement of responsibility, etc. | Hadeer Mohamed Nasr Eldin Ibrahim Azab ; Supervised Gamal Hassan Eltagy , Shereif Nabhan Kaddah , Wessam Mohamed Mahmoud |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم النتائج الإكلينيكية عقب اجراء تحويل خارجى جزئى لمسار العصارة الصفراوية لدى الاطفال المصابين بالركود الصفراوى داخل الكبد |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Hadeer Mohamed Nasr Eldin Ibrahim Azab , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 99 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Progressive familial intrahepatic cholestasis (PFIC) and Allagille syndrome (AGS) are hereditary cholestatic diseases that cause jaundice, severe debilitating life-limiting pruritus refractory to maximal medical treatment, and progressive liver damage. Surgical interruption of the enterohepatic circulation is considered a mainstay of alleviating distressing symptoms and delay progression to cirrhosis in cholestatic diseases including AGS and PFIC disease. Several strategies for diverting bile flow, including Partial external biliary diversion (PEBD), have been demonstrated. PEBD is considered an effective procedure with low morbidity and mortality. Objectives: Evaluate the effect of PEBD on pruritus, liver disease progression, growth, and life quality in children with chronic intrahepatic cholestasis. Methods: A prospective case series in which all patients with PFIC and AGS who underwent PEBD from July 2019 to July 2021 were included. Patients received medical treatment prior to biliary diversion and showed no improvement. The follow-up was conducted with pruritus assessment, bile acid level, and liver function tests. To determine the short-term effects of PEBD, clinical and laboratory workups, including growth data and quality of life, were reviewed. Partial internal drainage was offered for the patients who refused external diversion. Results: Seven patients underwent PEBD (5 with PFIC and 2 with AGS). The pre and post-PEBD clinical and laboratory assessments were compared. A remarkable statistical improvement was detected in pruritus score, bile acid level, and health-related quality of life assessment score. Amelioration of existing preoperative growth failure.The downscaling in the bilirubin level was not statistically significant. Moreover, there was no influential difference in the other liver function tests |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Allagille syndrome |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Intractable pruritus |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Progressive familial intrahepatic cholestasis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gamal Hassan Eltagy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shereif Nabhan Kaddah , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wessam Mohamed Mahmoud , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.Ph.D.2021.Ha.E | 01010110084874000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.Ph.D.2021.Ha.E | 01020110084874000 | 22.09.2023 | CD - Rom | 84874.CD |