Pre-implantation genetic screening (PGS) for common abnormalities in human embryos / (Record no. 83355)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03050cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032854.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211129s2021 ua do f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.25.M.Sc.2021.Mi.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mina Maher Mahny Mossad |
| 245 10 - TITLE STATEMENT | |
| Title | Pre-implantation genetic screening (PGS) for common abnormalities in human embryos / |
| Statement of responsibility, etc. | Mina Maher Mahny Mossad ; Supervised Saeed Abdelrahman Mostafa , Abdelwahab Abubakr Elghareeb , Ahmed Mohamed Mostafa Eelhalwagy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الفحص الجينى ما قبل الزرع للتشوهات الشائعة لأجنة الانسان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mina Maher Mahny Mossad , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 76 P. : |
| Other physical details | charts , photoghraphs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Pre-implantation genetic screening (PGS) aims to help couples lower the risks of transmitting genetic defects to their offspring, this technology has been employed as an embryo selection tool for patients undergoing in vitro fertilization, screening as many chromosomes as possible, in the hope that selecting chromosomally normal embryos will lead to higher implantation and decreased miscarriage rates. Material is collected from the oocyte (polar body), day three old embryo, or increasingly often, from the trophectoderm of a blastocyst. Selection of the diagnostic method depends on the testing center, but methods such as aCGH (Comparative Genomic Hybridization Array) and NGS (Next-Generation Sequencing) are supposed to have the highest reliability and precision.This paper presents a review of the most common abnormalities in human embryos.This study was conducted on 100 infertile women undergoing ICSI cycles with poor prognosis; poor responder women whose age is 27 or more, required 375 I.U. of gonadotropin or more per day to well stimulate their follicles and with history of previous failed ICSI. PGS was performed for 611 embryos for 24 chromosomes. The result showing a significant negative correlation between age and the Euploid embryo with P-value < 0.05. When the age increase there is a notable decrease in the euploid embryo.The highest common abnormalities were occurred in chromosomes number 13, 18, 19 and 22. In conclusion, our results suggest that Preimplantation genetic screening enhances molecular anomalies such as chromosomal abnormalities in patients with poor prognosis and should be offered to them as a routine |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ICSI |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Next Generation Sequencing |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Preimplantation Genetic Screening |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abdelwahab Abubakr Elghareeb , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mohamed Mostafa Eelhalwagy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Saeed Abdelrahman Mostafa , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.25.M.Sc.2021.Mi.P | 01010110084875000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.25.M.Sc.2021.Mi.P | 01020110084875000 | 22.09.2023 | CD - Rom | 84875.CD |