MARC details
000 -LEADER |
fixed length control field |
02471cam a2200313 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
211212s2021 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.12.08.M.Sc.2021.Em.A |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Eman Gamal sayed Ahmed |
245 10 - TITLE STATEMENT |
Title |
Analytical determination of some pharmaceutical compounds using different / |
Statement of responsibility, etc. |
Eman Gamal sayed Ahmed ; Supervised Mahmoud Sabry Rizk , Fatehy Mohamed Abdelhaleem |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
التقدير التحليلى لبعض المركبات الصيدلانية باستخدام مجسات مختلفة |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Eman Gamal sayed Ahmed , |
Date of publication, distribution, etc. |
2021 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
64 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Analytical Chemistry |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Two developed electrochemical biosensors were constructed for potentiometric determination of Ivabradine hydrochloride (IVB) in physiological fluids. The carbon-paste electrodes (CPEs) were constructed using nitrophenyl octyl ether as a plasticizer, graphite as source of carbon, Fe₂O₃ nanoparticles decorated multiwalled carbon nanotubes (Fe₂O₃@MWCNTs) as a modifier, t-butyl calixarene (t-BCX) or tailored molecularlyimprinted polymer (MIP) as ionophores. Loading the Fe2O3@MWCNTs into the CPEs increases the sensitivity and detection limit of the biosensors comparing with loading unmodified MWCNTs. MIP- and t-BCX-based CPEs exhibit Nernstian response of 56.0 and 58.9 mV decade-1 over drug concentration ranges of 10-3-10-8 and 10-3-10-7 M with detection limits of 9.8{u00D7}10-8 and 3.6{u00D7}10-8 M, respectively. Cavities in MIP and t-BCX are suitable for IVB masking with different complexing strengths, which were estimated by the sandwich membrane method (SMM). The developed biosensors exhibit better selectivity and higher formation constant because the cavities are tailored and more fitted for IVB. The developed biosensors are Sensitive for IVB determination in urine, serum and pharmaceutical preparations (Savapran®) |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Carbon-paste electrodes |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Electrochemical biosensors |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Lvabradine hydrochloride |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Fatehy Mohamed Abdelhaleem , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mahmoud Sabry Rizk , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |