In vitro antimicrobial activity of ceftazidime- avibactam tested against carbapenem resistant enterobacteriaceae and pseudomonas aeruginosa clinical isolates / (Record no. 83767)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02892cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032906.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220102s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.07.Ph.D.2021.Am.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amany Mahmoud Ahmed Mohamed |
| 245 10 - TITLE STATEMENT | |
| Title | In vitro antimicrobial activity of ceftazidime- avibactam tested against carbapenem resistant enterobacteriaceae and pseudomonas aeruginosa clinical isolates / |
| Statement of responsibility, etc. | Amany Mahmoud Ahmed Mohamed ; Supervised Mona Mohieeden Abdelhaleem , Amal Mohamed Sayed , Doaa Mohammad Ghaith |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | اختبار النشاط المضاد للميكروبات لعقار سيفتازديم افيبكتام داخل المعمل ضد البكتيريا المعوية المقاومة للكاربابينيم وسودوموناس اريوجونوزا للعزلات المرضية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Amany Mahmoud Ahmed Mohamed , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 129 P . : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Backgroung: The global spread of Carbapenem resistance organisms (CRO) has become a major public health concern especially regarding limited treatment options. Ceftazidime-avibactam (CZA) is a promising therapy for CRO causing infections Aim of work: we aimed to determine the prevalence of carbapenem resistant Enterobacteriaceae and Pseudomonas aeruginosa among clinical isolates and to investigate the in vitro antimicrobial susceptibility of CZA. Methods: Our study was conducted at Cairo university specialized pediatric hospital over one year. A total of 320 isolates were included. CZA.susceptibility testing was done disk diffusion method.The presence of carbapenemases was detected in 170 isolates by modified carbapenem inactivation method (mCIM) and multiplex PCR tests. Results: Prevalence of the prevalence of carbapenem resistant Enterobacteriaceae and Pseudomonas aeruginosa clinical isolates was 72.6%. Among our isolates, 78.8% were Klebsiella pneumoniae. The most frequently detected carbapenemase genes were blaNDM in 70.0% isolates, followed by blaOXA-48 in 67.6% and blaKPC in 16.5% isolates. CZA active against 30.0% of isolates Conclusion: multiplex PCR is sensitive and specific method for carbapenamase detection. CZA exhibited a fairly susceptible rate among our CRO |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Avibactam |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ceftazidime |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CRO |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amal Mohamed Sayed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mohammad Ghaith , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Mohieeden Abdelhaleem , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.07.Ph.D.2021.Am.I | 01010110085107000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.07.Ph.D.2021.Am.I | 01020110085107000 | 22.09.2023 | CD - Rom | 85107.CD |