Recent assessment approaches for detection of genotoxicity of some food additives in rats / (Record no. 83957)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02790cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032912.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220113s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.15.Ph.D.2021.Ah.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mohamed Bahy Eldien |
| 245 10 - TITLE STATEMENT | |
| Title | Recent assessment approaches for detection of genotoxicity of some food additives in rats / |
| Statement of responsibility, etc. | Ahmed Mohamed Bahy Eldien ; Supervised Mohamed Hashem , Khaled Aboelsooud , Yahia Abdelhamid Badr |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | طرق تقييم حديثة للكشف عن السمية الجينية لبعض أضافات الاغذية فى الجرزان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Mohamed Bahy Eldien , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 142 P . : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Veterinary Pharmacology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present study assessed the long-term daily administration of Titanium dioxide "TiO₂, E1713 & Acrylamide (ACR). Titanium dioxide and acrylamide are widely used as a food additives that exists in various everyday food products all over the world together with vast applications in cosmetics and industry. However, several toxicological issues, particularly after oral exposure. This study was planned to investigate the effect of oral exposure through oral gavage once daily for 90 consecutive days to two doses of TiO₂ and ACR which are (20 or 40 mg/kg bwt) AND (1 or 2 mg/kg b.wt.) respectively on the blood components, immunity, cytotoxic, and genotoxic indicators. The results revealed that a dose-dependent make leukopenia, eosinophilia, neutrophilia, and thrombocytopenia were noted. Also, the immunoglobins G (IgG) and IgM were significantly elevated the lysozyme levels, nitric oxide concentration, and phagocytic activity, immunoglobulin levels were significantly depleted. A significant reduced in lymphocyte proliferation but elevated LDH activity was prominent finally a marked increase in CD4 and CD8 immunolabeling was evident. Overall, these results indicated that TiO₂ and ACR exert hepatotoxic and immunotoxic effects with long-term exposure. these results indicated that the two-food additives could induce hematotoxicity, genotoxic, and immunotoxic alterations with exposure for long durations |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Acrylamide |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Immune function |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Titanium dioxide |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Khaled Aboelsooud , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Hashem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yahia Abdelhamid Badr , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.15.Ph.D.2021.Ah.R | 01010110085268000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.15.Ph.D.2021.Ah.R | 01020110085268000 | 22.09.2023 | CD - Rom | 85268.CD |