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Vascular endothelial growth factor and her - 2 / neu in breast cancer / Mona Mohamed Abdelhakim ; Supervised Hamdy Mahmoud Hassaneen , Samar Kamal Kassim , Mohamed Ali Eldesoukey

By: Contributor(s): Language: Eng Publication details: Cairo : Mona Mohamed Abdelhakim , 2004Description: 167P : ill ; 30cmOther title:
  • دراسة عامل النمو الغشائى البطانى الوعائى والهير - 2 نيو فى حالات سرطان الثدي [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty Of Science - Department Of Biochemistry Summary: Breast cancer represents an important problem in Women oncology A growing tumor induces the host endothelial cells to proliferate and supply the requisite vascular support allowing tumor development Vascular endothelial growth factor (VEGF) and HER2 - neu have been demonstrated to induce angiogenesis in epithelial tumors , this study included 45 tumors from patients with breast cancer in different grades and stages , in addition to 18 samples of benign breast lesions VEGF has been measured in the cytosolic fractions using enzyme immunoassay Tissue HER2 - neu was assessed using immunohistochemistry for its protein VEGF mean rank was significantly higher in breast cancer tumors compared to benign lesions (P=0001) Eleven samples were positive for Her2 - neu of them were in malignant group , with highest frequency in grade (IIIII) of the disease (11 / 45 , 25
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.M.Sc.2004.Mo.V. (Browse shelf(Opens below)) Not for loan 01010110043798000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.M.Sc.2004.Mo.V. (Browse shelf(Opens below)) Not for loan 01020110043798000

Thesis (M.Sc.) - Cairo University - Faculty Of Science - Department Of Biochemistry

Breast cancer represents an important problem in Women oncology A growing tumor induces the host endothelial cells to proliferate and supply the requisite vascular support allowing tumor development Vascular endothelial growth factor (VEGF) and HER2 - neu have been demonstrated to induce angiogenesis in epithelial tumors , this study included 45 tumors from patients with breast cancer in different grades and stages , in addition to 18 samples of benign breast lesions VEGF has been measured in the cytosolic fractions using enzyme immunoassay Tissue HER2 - neu was assessed using immunohistochemistry for its protein VEGF mean rank was significantly higher in breast cancer tumors compared to benign lesions (P=0001) Eleven samples were positive for Her2 - neu of them were in malignant group , with highest frequency in grade (IIIII) of the disease (11 / 45 , 25

Issued also as CD

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