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Perioperative analgesic efficiency of ultrasound-guided quadratus lumborum block versus epidural analgesia in bladder cancer patients undergoing radical cystectomy / by Mohamed Sayed Mohamed Rawi ; under supervision of Dr. Khaled Abdelhamid Mostafa, Dr. Dina Nabil Abbas, Dr. Ahmed Hussein Bakeer.

By: Contributor(s): Material type: TextTextLanguage: English Summary language: English, Arabic Producer: 2022Description: 119 pages : color illustrations ; 25 cm. + CDContent type:
  • text
Media type:
  • Unmediated
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  • volume
Other title:
  • كفاءة تسكين الألم ما حول الجراحة باستخدام تخدير العضلة الرباعية القطنية الموجه بالموجات فوق الصوتية بالمقارنة مع تخدير فوق األم الجافية في عمليات استئصال المثانة الجذري لمرضى سرطان المثانة
Subject(s): DDC classification:
  • 616.99462 21
Online resources: Available additional physical forms:
  • Issues also as CD.
Dissertation note: Thesis (Ph.D)-Cairo University,2022. Summary: Multimodal analgesia is currently used for perioperative pain management after Radical cystectomy (RC). This study aimed to compare quadratus lumborum block (QLB) and thoracic epidural block (TEA) in patients subjected to RC. Methods: This prospective randomized controlled study included 34 patients with bladder cancer subjected to RC under general anesthesia, divided into two groups. The Quadratus Group (n=17) underwent bilateral ultrasound-guided continuous QLB, and the Epidural Group (n=17) underwent continuous TEA. The primary outcome was pain intensity measured by VAS score, and the secondary outcomes were total morphine consumption during the first 48 hours after surgery, postoperative nausea score, and patient satisfaction. Results: There were no differences between the two groups in postoperative VAS scores starting immediately after surgery up to 48 hours. Reduction of VAS score after QLB was delayed compared to that after TEA. The two groups have a comparable number of patients requesting rescue analgesia (p = 0.271) and the total postoperative morphine consumption (p = 0.976) in the remaining patients. The nausea score was significantly lower in the Quadratus Group than in the Epidural Group (p = 0.020). There was no significant difference between the two groups in the satisfaction score (p=0.612). Few mild complications were detected in the two studied groups. Conclusion: QLB and TEA are safe and effective in managing postoperative pain after radical cystectomy with similar analgesic profiles. QLB was more effective in reducing postoperative nausea and vomiting. Summary: سرطان المثانة هو نوع شائع من انواع السرطان على مستوى العلام و فى مصر كذلك مع زيادة فى نسبة الاصابة بين الذكور و النوع الشائع م نسرطان المثانة على مستوى العالم هو سرطان الخلايا الانتقالية خطط التعامل الطبى مع سرطان المثانة تتفاوت بدرجة كبيرة حسب نوع المرض و المرحلة المرضية عند التشخيص بينما يستجيب مرضى سرطانة المثانة من النوع غير المتداخل مع العضلات للعلاج الكيمياوى الموضعى و العلاج الاشعاعى مع تدخلات جراحية صغرى فان مرضى سرطان المثانة من النوع المتداخل مع العضلات يخضعون تقليديا للعلاج الكيماوى المعتمد على البلاتين متبوعا بعملية اسئصال جذرى للمثانة
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.01.Ph.D.2022.Mo.P (Browse shelf(Opens below)) Not for loan 01010110087271000
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Cai01.19.01.Ph.D.2021.Em.C Comparative study of the effect of propofol-based anestheseia versus low dose propofol with less Than Half MAC sevoflurane anesthesia on intraoperative trans-cranial motor evoked potential during neoplastic & non-neoplastic spine surgeries / Cai01.19.01.Ph.D.2021.Em.C Comparative study of the effect of propofol-based anestheseia versus low dose propofol with less Than Half MAC sevoflurane anesthesia on intraoperative trans-cranial motor evoked potential during neoplastic & non-neoplastic spine surgeries / Cai01.19.01.Ph.D.2021.Mo.E Efficacy of Ultrasound‑Guided Quadratus Lumborum Block type II as a Perioperative Analgesic Technique for Pelvic Cancer Surgeries / Cai01.19.01.Ph.D.2022.Mo.P Perioperative analgesic efficiency of ultrasound-guided quadratus lumborum block versus epidural analgesia in bladder cancer patients undergoing radical cystectomy / Cai01.19.01.Ph.D.2022.No.C Comparative study between modified pectoral nerve block with adding ketamine to bupivacaine versus modified pectoral nerve block with bupivacaine in patients undergoing modified radical mastectomy / Cai01.19.01.Ph.D.2023.Ah.E Effects Of Adding Dexamethasone Plus Ketamine To Bupivacaine For Ultrasound Guided Serratus Plane Block As Analgesia In Major Breast Surgery/ Cai01.19.01.Ph.D.2023.Ho.V. The Value Of Motor Index In Predicting The Success Of Radiofrequency Treatment Of Trigeminal Neuralgia: A Retrospective Study /

Thesis (Ph.D)-Cairo University,2022.

Bibliography: p. 95-119.

Multimodal analgesia is currently used for perioperative pain management after Radical cystectomy (RC). This study aimed to compare quadratus lumborum block (QLB) and thoracic epidural block (TEA) in patients subjected to RC. Methods: This prospective randomized controlled study included 34 patients with bladder cancer subjected to RC under general anesthesia, divided into two groups. The Quadratus Group (n=17) underwent bilateral ultrasound-guided continuous QLB, and the Epidural Group (n=17) underwent continuous TEA. The primary outcome was pain intensity measured by VAS score, and the secondary outcomes were total morphine consumption during the first 48 hours after surgery, postoperative nausea score, and patient satisfaction.
Results: There were no differences between the two groups in postoperative VAS scores starting immediately after surgery up to 48 hours. Reduction of VAS score after QLB was delayed compared to that after TEA. The two groups have a comparable number of patients requesting rescue analgesia (p = 0.271) and the total postoperative morphine consumption (p = 0.976) in the remaining patients. The nausea score was significantly lower in the Quadratus Group than in the Epidural Group (p = 0.020). There was no significant difference between the two groups in the satisfaction score (p=0.612). Few mild complications were detected in the two studied groups.
Conclusion: QLB and TEA are safe and effective in managing postoperative pain after radical cystectomy with similar analgesic profiles. QLB was more effective in reducing postoperative nausea and vomiting.

سرطان المثانة هو نوع شائع من انواع السرطان على مستوى العلام و فى مصر كذلك مع زيادة فى نسبة الاصابة بين الذكور و النوع الشائع م نسرطان المثانة على مستوى العالم هو سرطان الخلايا الانتقالية خطط التعامل الطبى مع سرطان المثانة تتفاوت بدرجة كبيرة حسب نوع المرض و المرحلة المرضية عند التشخيص بينما يستجيب مرضى سرطانة المثانة من النوع غير المتداخل مع العضلات للعلاج الكيمياوى الموضعى و العلاج الاشعاعى مع تدخلات جراحية صغرى فان مرضى سرطان المثانة من النوع المتداخل مع العضلات يخضعون تقليديا للعلاج الكيماوى المعتمد على البلاتين متبوعا بعملية اسئصال جذرى للمثانة

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