The association of Helicobacter pylori infection with estimated cardiovascular risk among patients attending Cairo University outpatient clinics / by Marina Shaker Riad Girgis ; Supervisors DR. Inas Talaat Abdelhamid, DR. Eman Ismail Mohamed Raslan, DR. Samar Saad Mohamed Mostafa.

By:

Marina Shaker Riad Girgis [preparation.]

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Material type: Text

TextLanguage: English Summary language: English Spoken language: Arabic Producer: 2023Description: 116 pages : illustrations ; 25 cm. + CDContent type:

text

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Unmediated

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volume

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/ ارتباط العدوى بالبكتيريا الحلزونية وخطر الإصابة بأمراض القلب والأوعية الدموية المقدرة بين المرضى الذين يترددون على العيادات الخارجية بجامعة القاهرة [Added title page title]

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DDC classification:

616.12

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Dissertation note: Thesis (M.Sc.)-Cairo University, 2023. Summary: H. pylori infection is one of the world‘s commonest health problems, infecting more than 50% of the global population. In Egypt, the prevalence is estimated to be 80%. Preliminary studies suggest an association between H. pylori infection and increased cardiovascular risk, and latest guidelines recommend eradication of H. pylori in patients with atherosclerosis. Aim: To assess the association between H. pylori infection and the risk of cardiovascular disease and the effect of H. pylori infection on bio-psycho-social health. Methods: This is a case-control study conducted on two groups; 46 of participants complaining of dyspepsia with high cardiovascular risk (cases) and 46 of participants complaining of dyspepsia with low cardiovascular risk (controls) underwent a structured interview using a pre-designed questionnaire .We evaluated the association between H. pylori infection and cardiovascular risk assessed by pooled cohort equation using logistic regression. Multivariate logistic regression tests were used by adjusting age, sex, BMI, lipid, smoking, DM, and HTN. Results: A total of 92 patients participated in this study. Comparing case and control groups revealed a significant increase in H. pylori infection (p= 0.04) in case group patients (74%) compared to control group patients (63%). H. pylori infection was significantly associated with increased CVD risk (OR 1.661, 95%CI 0.682-4.043; P < 0.0001) and remained so after multivariable adjustment. There were significant differences between both groups of H. pylori and gender (P= 0.001), level of education (p = 0.001), residence (P=0.04), social class (P=0.01) and smoking (P= 0.0001) Conclusions: H. pylori infection may be one of the probable risk factors for CVD independent of history BMI, dyslipidemia, smoking, DM, and HTN.Summary: تشير الدراسات الأولية إلى وجود علاقة بين إيجابية الحلزونية البوابية ومخاطر القلب والأوعية الدموية. كان الهدف هو تقييم العلاقة بين عدوى الملوية البوابية وأمراض القلب والأوعية الدموية وعوامل الخطر الخاصة بها وتأثير الإصابة بالبكتيريا الحلزونية على الصحة البيولوجية النفسية والاجتماعية. 92 مشاركًا يشكون من عسر الهضم خضعوا لمقابلة منظمة باستخدام استبيان مصمم مسبقًا يغطي الشخصيات الاجتماعية والديموغرافية والبيانات الطبية ومقاييس الجسم البشري والفحص ، مما يدل على أن إيجابية الحلزونية البوابية مرتبطة بارتفاع مخاطر القلب والأوعية الدموية.

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Item type	Current library	Home library	Call number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01 11 35 M.Sc 2023 Ma.A (Browse shelf(Opens below))	Not for loan	01010110088413000

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Thesis (M.Sc.)-Cairo University, 2023.

Bibliography: pages 76-94.

H. pylori infection is one of the world‘s commonest health
problems, infecting more than 50% of the global population. In Egypt, the
prevalence is estimated to be 80%. Preliminary studies suggest an association
between H. pylori infection and increased cardiovascular risk, and latest guidelines
recommend eradication of H. pylori in patients with atherosclerosis.
Aim: To assess the association between H. pylori infection and the risk of
cardiovascular disease and the effect of H. pylori infection on bio-psycho-social
health.
Methods: This is a case-control study conducted on two groups; 46 of participants
complaining of dyspepsia with high cardiovascular risk (cases) and 46 of
participants complaining of dyspepsia with low cardiovascular risk (controls)
underwent a structured interview using a pre-designed questionnaire .We evaluated
the association between H. pylori infection and cardiovascular risk assessed by
pooled cohort equation using logistic regression. Multivariate logistic regression
tests were used by adjusting age, sex, BMI, lipid, smoking, DM, and HTN.
Results: A total of 92 patients participated in this study. Comparing case and
control groups revealed a significant increase in H. pylori infection (p= 0.04) in
case group patients (74%) compared to control group patients (63%). H. pylori
infection was significantly associated with increased CVD risk (OR 1.661, 95%CI
0.682-4.043; P < 0.0001) and remained so after multivariable adjustment. There
were significant differences between both groups of H. pylori and gender (P=
0.001), level of education (p = 0.001), residence (P=0.04), social class (P=0.01)
and smoking (P= 0.0001)
Conclusions: H. pylori infection may be one of the probable risk factors for CVD
independent of history BMI, dyslipidemia, smoking, DM, and HTN.

تشير الدراسات الأولية إلى وجود علاقة بين إيجابية الحلزونية البوابية ومخاطر القلب والأوعية الدموية. كان الهدف هو تقييم العلاقة بين عدوى الملوية البوابية وأمراض القلب والأوعية الدموية وعوامل الخطر الخاصة بها وتأثير الإصابة بالبكتيريا الحلزونية على الصحة البيولوجية النفسية والاجتماعية. 92 مشاركًا يشكون من عسر الهضم خضعوا لمقابلة منظمة باستخدام استبيان مصمم مسبقًا يغطي الشخصيات الاجتماعية والديموغرافية والبيانات الطبية ومقاييس الجسم البشري والفحص ، مما يدل على أن إيجابية الحلزونية البوابية مرتبطة بارتفاع مخاطر القلب والأوعية الدموية.

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