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Comparative Study Between Oral and Vaginal Misoprostol for Induction of Labor in Nulliparous Pregnant Women at or Beyond Completed 41 Weeks / By Elsayed Fekry Elsayed Omran; Under Supervision of DR. Heba Aly El Sawah, DR. Marwa Fouad Sharaf, DR. Mahmoud Ahmed Ismail AbdElhameed

By: Contributor(s): Material type: TextTextLanguage: English Summary language: English, Arabic Producer: 2023Description: 73 pages : illustrations ; 25 cm. + CDContent type:
  • text
Media type:
  • Unmediated
Carrier type:
  • volume
Other title:
  • دراسة الفرق بين إعطاء عقار الميزوبروستول بالفم أو بالمهبل لتحريض الولادة في السيدات اللاتي لم ينجبن من قبل وأتممن 41 أسبوع من الحمل [Added title page title]
Subject(s): DDC classification:
  • 618.1
Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) -Cairo University, 2023. Summary: Background: Although, vaginal application of misoprostol has been validated as a reasonable mean of induction, there is a patient resistance to digital examination and there is a risk of ascending infection. So, oral administration of misoprostol for labor induction was tried. Aim and objectives: To compare efficacy and safety of vaginal misoprostol with oral misoprostol for induction of labor in nulliparouspregnantwomenatorbeyondcompleted41weeks. Subjects and methods: Eighty nulliparous pregnant women who were candidate for labor induction at or beyond completed 41 weeks divided into two groups: (Group 1):40 pregnant women who received vaginal misoprostol in a dose of 25μg and repeated every 6 hours if no response was achieved with a maximum of 4 doses, (Group 2):40 pregnant women who received oral misoprostol in a dose of 25μg and repeated every 6 hours if no response was achieved with a maximum of 4 doses. Results: There was no statistically significant difference between oral& vaginal misoprostol regarding induction to active stage of labor, induction to delivery interval, cesarean deliveries, number of doses needed, maternal or neonatal complications. On the other hand, oxytocin augmentation was significantly lower in the vaginal group. Conclusion: 25 mg orally administered misoprostol is similarly effective & safe as 25 mg vaginal misoprostol to induce labor in nulliparous women with an unripe cervix at or beyond completed 41weeks. Summary: كانت الحاجة لزيادة تحفيز المخاض باستخدام الأوكسيتوسين أعلى بشكل يعتد به في مجموعة الميزوبروستول الفموى بالمقارنة مع مجموعة الميزوبروستول المهبلى. إن تناول 25 ملغ من الميزوبروستول عن طريق الفم فعالة وآمنة بشكل مشابه مثل تناول 25 ملغ من الميزوبروستول عن طريق المهبل للحث على المخاض عند النساء اللاتي لم ينجبن من قبل وأتممن 41 أسبوعًا من الحمل. ومع ذلك، وُجد أن الحاجة إلى تحفيز المخاض باستخدام الأوكسيتوسين أعلى لدى النساء اللائي استخدمن الميزوبروستول الفموي
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.15.M.Sc.2023.El.C. (Browse shelf(Opens below)) Not for loan 01010110088633000

Thesis (M.Sc.) -Cairo University, 2023.

Bibliography: pages 63-73.

Background: Although, vaginal application of misoprostol has been
validated as a reasonable mean of induction, there is a patient resistance to
digital examination and there is a risk of ascending infection. So, oral
administration of misoprostol for labor induction was tried.
Aim and objectives: To compare efficacy and safety of vaginal
misoprostol with oral misoprostol for induction of labor in
nulliparouspregnantwomenatorbeyondcompleted41weeks.
Subjects and methods: Eighty nulliparous pregnant women who were
candidate for labor induction at or beyond completed 41 weeks divided into
two groups: (Group 1):40 pregnant women who received vaginal
misoprostol in a dose of 25μg and repeated every 6 hours if no response
was achieved with a maximum of 4 doses, (Group 2):40 pregnant women
who received oral misoprostol in a dose of 25μg and repeated every 6 hours
if no response was achieved with a maximum of 4 doses.
Results: There was no statistically significant difference between oral&
vaginal misoprostol regarding induction to active stage of labor, induction
to delivery interval, cesarean deliveries, number of doses needed, maternal
or neonatal complications. On the other hand, oxytocin augmentation was
significantly lower in the vaginal group.
Conclusion: 25 mg orally administered misoprostol is similarly effective
& safe as 25 mg vaginal misoprostol to induce labor in nulliparous women
with an unripe cervix at or beyond completed 41weeks.

كانت الحاجة لزيادة تحفيز المخاض باستخدام الأوكسيتوسين أعلى بشكل يعتد به في مجموعة الميزوبروستول الفموى بالمقارنة مع مجموعة الميزوبروستول المهبلى. إن تناول 25 ملغ من الميزوبروستول عن طريق الفم فعالة وآمنة بشكل مشابه مثل تناول 25 ملغ من الميزوبروستول عن طريق المهبل للحث على المخاض عند النساء اللاتي لم ينجبن من قبل وأتممن 41 أسبوعًا من الحمل. ومع ذلك، وُجد أن الحاجة إلى تحفيز المخاض باستخدام الأوكسيتوسين أعلى لدى النساء اللائي استخدمن الميزوبروستول الفموي

Issued also as CD

Text in English and abstract in Arabic & English.

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