The short outcome of patients undergoing off-pump cabg using remote versus regional ischemic preconditioning / by Micheal Wagih Refaat Habib ; supervision of Prof. Dr. Ehab Mohamed Elshihy, Prof. Dr. Ahmed SalahEldin Fouad, Dr. Ashraf Mostafa Abd Raboh, Dr. Mahmoud Ahmad Zayed.

By:

Micheal Wagih Refaat Habib [preparation.]

Contributor(s):

Material type: Text

TextLanguage: English Summary language: English, Arabic Producer: 2023Description: 126 pages : illustrations ; 25 cm. + CDContent type:

text

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Unmediated

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volume

Other title:

/ النتائج المبكره للمرضى الذين يخضعون لعمليه توصيل شرايين القلب باستخدام تقنية القلب النابض باستخدام التحضير الموضعي للشرايين التاجيه مقابل التحضير من الاعضاء الطرفيه [Added title page title]

Subject(s):

DDC classification:

616.123

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Issues also as CD.

Dissertation note: Thesis (Ph.D)-Cairo University, 2023. Summary: Background: Ischemic preconditioning (IPC), defined as protection of the myocardium by inducing a short ischemic period before a subsequent longer period of ischemia Objective: To assess the short outcome of patients undergoing off-pump CABG using remote versus regional ischemic preconditioning & its effect on myocardial perfusion injury according to the cardiac enzymes & cardiac contractility by Echocardiogram. Patients and Methods: This is a prospective comparative study in which comparison of the short outcome of patients undergoing off-pump CABG between those who used remote and those using regional ischemic preconditioning (PC) and compare its effect on the myocardial perfusion injury according to both the cardiac enzymes and the cardiac contractility by Echocardiogram. The study involved 100 patients classified into two equal groups; group (A) used regional ischemic PC and group (B) used remote ischemic PC. They were 32 males (64%) and 18 females (36%) in group (A) and 35 males (70%) and 15 females (30%) in group (B). Results: Regarding postoperative cardiac enzymes serials of cardiac enzymes had been done in 12,24 and 72 hours postoperative and showed a significant decrease in both groups subsequently and showed nonsignificant difference (p >0.05) between both groups. However, both groups of the study showed significant reduction in serum Troponin levels as Hs-TnI in both groups postoperative values at 12 hours: were group (A) 0.365 group B 0.363, 24 hours: group (A)0.255 group B 0.253, 72 hours group (A)0.038, group (B)0.036 & at 120 hrs group (A) decreased to 0.026 & group B also decreased to 0.024. Conclusion: According to our study in comparison with other studies, it showed a great outcome in myocardial contractility and low incidence of cardiac reperfusion injury for those being applied ischemic preconditioning. Regarding to remote and regional ischemic preconditioning, there were no significant difference in myocardial protection, reperfusion injury or postoperative outcome, however remote precondition is technically safer to be applied than regional coronary occlusion

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Holdings
Item type	Current library	Home library	Call number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.05.Ph.D.2023.Mi.S (Browse shelf(Opens below))	Not for loan	01010110089388000

Thesis (Ph.D)-Cairo University, 2023.

Bibliography: pages 104-126.

Background: Ischemic preconditioning (IPC), defined as protection of the myocardium by inducing a short ischemic period before a subsequent longer period of ischemia
Objective: To assess the short outcome of patients undergoing off-pump CABG using remote versus regional ischemic preconditioning & its effect on myocardial perfusion injury according to the cardiac enzymes & cardiac contractility by Echocardiogram.
Patients and Methods: This is a prospective comparative study in which comparison of the short outcome of patients undergoing off-pump CABG between those who used remote and those using regional ischemic preconditioning (PC) and compare its effect on the myocardial perfusion injury according to both the cardiac enzymes and the cardiac contractility by Echocardiogram. The study involved 100 patients classified into two equal groups; group (A) used regional ischemic PC and group (B) used remote ischemic PC. They were 32 males (64%) and 18 females (36%) in group (A) and 35 males (70%) and 15 females (30%) in group (B).
Results: Regarding postoperative cardiac enzymes serials of cardiac enzymes had been done in 12,24 and 72 hours postoperative and showed a significant decrease in both groups subsequently and showed nonsignificant difference (p >0.05) between both groups. However, both groups of the study showed significant reduction in serum Troponin levels as Hs-TnI in both groups postoperative values at 12 hours: were group (A) 0.365 group B 0.363, 24 hours: group (A)0.255 group B 0.253, 72 hours group (A)0.038, group (B)0.036 & at 120 hrs group (A) decreased to 0.026 & group B also decreased to 0.024.
Conclusion: According to our study in comparison with other studies, it showed a great outcome in myocardial contractility and low incidence of cardiac reperfusion injury for those being applied ischemic preconditioning. Regarding to remote and regional ischemic preconditioning, there were no significant difference in myocardial protection, reperfusion injury or postoperative outcome, however remote precondition is technically safer to be applied than regional coronary occlusion

Issues also as CD.

Text in English and abstract in Arabic & English.

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