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Expression of hepatocyte paraffin 1 antibody and vascular endothelial growth factor in hepatocellular carcinoma and chronic viral hepatitis : an immunohistochemical study / Rabab Maamoun Salama ; Supervised Soheir Zakaria Mohamed Eissa , Nabil Mostafa Al Kadi , Maha Mahmoud Akl

By: Contributor(s): Language: English Publication details: Cairo : Rabab Maamoun Salama , 2007Description: 118 P. : ill. ; 25CmOther title:
  • اظهار هيب 1 وعامل النمو البطانى للاوعية الدموية فى مرضى اورام الكبد الاولية والالتهاب الكبدى الفيروسى المزمن : دراسة هيستو كيميائية مناعية [Added title page title]
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  • Issued as also CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine Summary: The prognosis of HCC patients is generally very poor , that's why early detection of patients with HCC became attractive and beneficial.HCC is generally well known to be extensively vascularized and the occurrence of primary intrahepatic and lung metastases suggests its mainly hematogenous dissemination.Therefore , it is possible that angiogenesis plays a pivotal role during hepatocellular carcinogenesis.VEGF expression is significantly associated with a higher proliferative index and may characterize progression towards higher proliferation in hepatocarcinogenesis.Using immunohistochemistry , the expression of VEGF is much stronger in tumor cells compared with hepatocytes in normal or cirrhotic liver and high expression of VEGF , especially under hypoxic conditions was reported in liver cirrhosis and viral hepatitis infection , which both predispose individuals to hepatocarcinogenesis
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.33.Ph.D.2007.Ra.E (Browse shelf(Opens below)) Not for loan 01010110047025000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.33.Ph.D.2007.Ra.E (Browse shelf(Opens below)) 47025.CD Not for loan 01020110047025000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine

The prognosis of HCC patients is generally very poor , that's why early detection of patients with HCC became attractive and beneficial.HCC is generally well known to be extensively vascularized and the occurrence of primary intrahepatic and lung metastases suggests its mainly hematogenous dissemination.Therefore , it is possible that angiogenesis plays a pivotal role during hepatocellular carcinogenesis.VEGF expression is significantly associated with a higher proliferative index and may characterize progression towards higher proliferation in hepatocarcinogenesis.Using immunohistochemistry , the expression of VEGF is much stronger in tumor cells compared with hepatocytes in normal or cirrhotic liver and high expression of VEGF , especially under hypoxic conditions was reported in liver cirrhosis and viral hepatitis infection , which both predispose individuals to hepatocarcinogenesis

Issued as also CD

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