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Synthesis of some fused pyrrolizine derivatives of anticipated biological activit / Ahmed Mahmoud Gouda ; Supervised Samir Mohamed Elmoghazy Aly , Mohamed Abd El azeem Mohamed , Awatef Elsaid Farag

By: Contributor(s): Language: Eng Publication details: Cairo : Ahmed Mahmoud Gouda , 2006Description: 113P : charts ; 30cmOther title:
  • تشييد بعض مشتقات البيروليزينات المكثفة من المتوقع ان يكون لها فاعليه بيولوجية [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutical Chemistry Summary: In addition 2 - amino - 1 - cyano - 6 , 7 - dihydro - 5H - pyrrolizine - 3 - carboxamide 66 was reacted with acid chloride , phenyl isocyanate and benzaldehyde to give 2 - acyl amino 69 , 2 - (3 - aryl ureido) 74 and 2 - benzylideneamino 70 derivatives respectively Hydrolysis of the cyano to carboxamide group was achieved using alkaline hydrogen peroxide The tricyclic derivatives pyrimido[4 , 5 - b]pyrrolizine 67 and pyrimido[5 , 4 - a]pyrrolizine 68 was obtained by refluxing compound 66 with ethyl chloroformate and formic acid respectively
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.M.Sc.2006.Ah.S. (Browse shelf(Opens below)) Not for loan 01010110046373000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.M.Sc.2006.Ah.S. (Browse shelf(Opens below)) 46373.CD Not for loan 01020110046373000

Thesis (M.Sc.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutical Chemistry

In addition 2 - amino - 1 - cyano - 6 , 7 - dihydro - 5H - pyrrolizine - 3 - carboxamide 66 was reacted with acid chloride , phenyl isocyanate and benzaldehyde to give 2 - acyl amino 69 , 2 - (3 - aryl ureido) 74 and 2 - benzylideneamino 70 derivatives respectively Hydrolysis of the cyano to carboxamide group was achieved using alkaline hydrogen peroxide The tricyclic derivatives pyrimido[4 , 5 - b]pyrrolizine 67 and pyrimido[5 , 4 - a]pyrrolizine 68 was obtained by refluxing compound 66 with ethyl chloroformate and formic acid respectively

Issued also as CD

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