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Synthesis of new pyrrole pyrazole pyrimidine and pyrrolopyrimidine derivatives carrying a sulfonamide moiety of expected antitumor activity : with studying the synergistic effect of y - irradiation / Marwa Galal Eldin Elgazzar ; Supervised Fatma Abdelfattah Ragab , Mostafa Mohamed Soliman Ghorab , Helmi Ismail Heiba

By: Contributor(s): Material type: TextTextLanguage: eng Publication details: Cairo : Marwa Galal Eldin Elgazzar , 2010Description: 164 P. : charts , facsimiles ; 25cmOther title:
  • تشييد مشتقات البيرول : البيرازول : البيريميدين والبيرولوبيريميدين الجديدة والتى تحتوى على مجموعة السلفوناميد المتوقع لها نشاطا كمضادلت للسرطان : ودراسة التأثير التحفيزى للتشعيع الجامى [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry Summary: In a search for new cytoloxic agents with improved antitumor activity some new pyrrole pyrazole pyrimidine and pyrrolo [2,3-d] pyrimidine derivatives bearing sulfonamide moiety were synthesized . All the newly synthesized compounds were subjected to in - vitro cytotoxic screening also the synergism of the synthesized compounds with radiation was studied . These new compounds were docked in the active site of the carbonic anhydrase enzyme
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2010.Ma.S (Browse shelf(Opens below)) Not for loan 01010110052727000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2010.Ma.S (Browse shelf(Opens below)) 52727.CD Not for loan 01020110052727000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

In a search for new cytoloxic agents with improved antitumor activity some new pyrrole pyrazole pyrimidine and pyrrolo [2,3-d] pyrimidine derivatives bearing sulfonamide moiety were synthesized . All the newly synthesized compounds were subjected to in - vitro cytotoxic screening also the synergism of the synthesized compounds with radiation was studied . These new compounds were docked in the active site of the carbonic anhydrase enzyme

Issued also as CD

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