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Molecular modeling , synthesis and antimicrobial activity of novel benzothiazole derivatives / Nashwa Ahmed Ibrahim Mansour ; Supervised Samir Mohamed ElMoghazy Aly , Safinaz ElSayed Abbas , Mohammad AbdulAzim Mohammad

By: Contributor(s): Language: Eng Publication details: Cairo : Nashwa Ahmed Ibrahim Mansour , 2006Description: 122P : ill ; 30cmOther title:
  • النمزجة الجزيئية و تشييد بعض مشتقات البنزوثيازول الجديدة من المتوقع ان يكون لها فاعلية ضد الميكروبات [Added title page title]
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Dissertation note: Thesis (PH.D.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutical Chemistry Summary: The present investigation comprises a general survey on the biological activities of benzothiazole derivativesTen known starting and intermediate compounds and fourteen new intermediates were preparedIn addition , forty one novel 2 , 6 - disubstituted and 2 - substituted aminobenzo? thiazole derivatives that classified into seven series had been synthesizedIn order to obtain the target compounds the following routes were adoptedA series of 2 - substituted amino - 6 - substituted aminocarbonyl - 1 , 3 - benzothiazol - 2 - ylaminomethanone (86a - c) was prepared by the reaction of 1 - (6 - amino - 1 , 3 - benzothiazol - 2 - yl) - 3 - substituted urea (85a - c) with the appropriate isocyanateThe 1 - [6 - (5 - amino - 4 - cyano - 1H - pyrazol - 1 - yl) - 1 , 3 - benzothiazol - 2 - yl] - 3 - phenylurea (88) was synthesized by the reaction of 1 - (6 - hydrazino - 1 , 3 - benzothiazol - 2 - yl) - 3 - phenylurea (87) and ethoxymethyl? enemalononitrile (97)
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Item type Current library Home library Call number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2006.Na.M. (Browse shelf(Opens below)) Not for loan 01010110046173000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2006.Na.M. (Browse shelf(Opens below)) Not for loan 01020110046173000

Thesis (PH.D.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutical Chemistry

The present investigation comprises a general survey on the biological activities of benzothiazole derivativesTen known starting and intermediate compounds and fourteen new intermediates were preparedIn addition , forty one novel 2 , 6 - disubstituted and 2 - substituted aminobenzo? thiazole derivatives that classified into seven series had been synthesizedIn order to obtain the target compounds the following routes were adoptedA series of 2 - substituted amino - 6 - substituted aminocarbonyl - 1 , 3 - benzothiazol - 2 - ylaminomethanone (86a - c) was prepared by the reaction of 1 - (6 - amino - 1 , 3 - benzothiazol - 2 - yl) - 3 - substituted urea (85a - c) with the appropriate isocyanateThe 1 - [6 - (5 - amino - 4 - cyano - 1H - pyrazol - 1 - yl) - 1 , 3 - benzothiazol - 2 - yl] - 3 - phenylurea (88) was synthesized by the reaction of 1 - (6 - hydrazino - 1 , 3 - benzothiazol - 2 - yl) - 3 - phenylurea (87) and ethoxymethyl? enemalononitrile (97)

Issued also as CD

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