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The impact of CYP2C9*3 and calumenin genetic polymorphisms on warfarin dose requirements / Rehab Helmy Mohammed Ibrahim ; Supervised Sanaa Omar Asaad , Neguib Zoheir Mostafa , Heba Sherif Kareem

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Rehab Helmy Mohammed Ibrahim , 2012Description: 122 P. : charts ; 25cmOther title:
  • تأثير التغير الجينى لكل من جين السيتوكروم (٢س٩) و جين الكاليومينين على ضبط جرعة الوارفارين [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Warfarin is one of the most widely used coumarin anticoagulants. However, its use is made difficult by the wide interindividual variation in dose required to achieve a therapeutic effect, the narrow therapeutic range, and the risk of serious bleeding. Warfarin dose requirement, which varies 20-fold, is influenced by factors such as intake of vitamin K, ethnicity, illness, age, gender, concurrent medication, body mass index and genetic factors
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2012.Re.I (Browse shelf(Opens below)) Not for loan 01010110057539000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2012.Re.I (Browse shelf(Opens below)) 57539.CD Not for loan 01020110057539000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Warfarin is one of the most widely used coumarin anticoagulants. However, its use is made difficult by the wide interindividual variation in dose required to achieve a therapeutic effect, the narrow therapeutic range, and the risk of serious bleeding. Warfarin dose requirement, which varies 20-fold, is influenced by factors such as intake of vitamin K, ethnicity, illness, age, gender, concurrent medication, body mass index and genetic factors

Issued also as CD

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