Thesis (M.Sc.) - Cairo University - Faculty of Medicine. - Department of Internal Medicine

Stem cell transplantation offers potentially curative therapy for patients with myelodysplastic syndrome. A broad scale regimens, ranging from "modified" conventional to reduced intensity to non-myeloablative regimens, has been developed and used successfully; one size does not appear to fit all. Rather, patient age, co-morbid conditions, disease stage, ferretin level, presence and severity of myelofibrosis, non-transplant chemotherapy, type of donor, source of stem cell, and other factors, all affect the decision regarding transplantation and impact on outcome

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