Synthesis of new thiazole derivatives bearing a sulfonamide moiety of expected anticancer and radiosensitizing activities / Sara Shaban Ibrahim Mohamed ; Supervised Mohamed Abdelrahman Shaaban , Helmy Imail Heiba , Hanan Mohamed Refaat

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Sara Shaban Ibrahim Mohamed

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TextLanguage: English Publication details: Cairo : Sara Shaban Ibrahim Mohamed , 2012Description: 123P. : charts , facsimiles ; 25cmOther title:

تحضير مشتقات الثيازول الجديدة والتى تحتوى على مجموعة السلفوناميد والمتوقع لها نشاطا كمضادات للسرطان وكمحفزات للاشعاع [Added title page title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry Summary: In a search for new cytotoxic agents with improved antitumor activity and selectivity , some new pyranothiazole and thiazolopyranopyimidine derivatives bearing sulfonamide moiety were synthesized . The newly synthesized compounds were evaluated for their antitumor activity alone and in combination with y - irradiation . These new compounds were docked inside the active site of carbonic anhydrase II to predict their mechanism of action

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Item type	Current library	Home library	Call number	Copy number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.08.04.M.Sc.2012.Sa.S (Browse shelf(Opens below))		Not for loan	01010110059319000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.08.04.M.Sc.2012.Sa.S (Browse shelf(Opens below))	59319.CD	Not for loan	01020110059319000

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Previous	Cai01.08.04.M.Sc.2012.Am.D Design and synthesis of 5 - cyano - 6 substituted phenyl - 2 - thiouracll derivatives as anticancer and antimicrobial agents /	Cai01.08.04.M.Sc.2012.Am.D Design and synthesis of 5 - cyano - 6 substituted phenyl - 2 - thiouracll derivatives as anticancer and antimicrobial agents /	Cai01.08.04.M.Sc.2012.Sa.S Synthesis of new thiazole derivatives bearing a sulfonamide moiety of expected anticancer and radiosensitizing activities /	Cai01.08.04.M.Sc.2012.Sa.S Synthesis of new thiazole derivatives bearing a sulfonamide moiety of expected anticancer and radiosensitizing activities /	Cai01.08.04.M.Sc.2012.Ya.N New approaches for the synthesis of thiophene derivatives and their biological evaluation /	Cai01.08.04.M.Sc.2012.Ya.N New approaches for the synthesis of thiophene derivatives and their biological evaluation /	Cai01.08.04.M.Sc.2012.Ya.S Synthesis and evaluation of the anticonvulsant activity of bivalent ligands derived from phenytoin /	Next

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry

In a search for new cytotoxic agents with improved antitumor activity and selectivity , some new pyranothiazole and thiazolopyranopyimidine derivatives bearing sulfonamide moiety were synthesized . The newly synthesized compounds were evaluated for their antitumor activity alone and in combination with y - irradiation . These new compounds were docked inside the active site of carbonic anhydrase II to predict their mechanism of action

Issued also as CD

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