Evaluation of the role of ADAMTS13 activity and anti-ADAMTS13 autoantibodies in the pathogenesis and prognosis of thrombotic microangiopathy patients on plasma exchange therapy / Ahmed Mohamed Ali Abdelhafez ; Supervised Azza Ahmed Aboulenein , Osama Ahmed Khalafallah , Nermeen Ahmed Eldesouki
Material type:
- و نشاط الأجسام المضادة لهذا الإنزيم فى حالات تخثر الدم فى الأوعية الدقيقة و مدى استجابتها لجلسات تغيير البلازما المتعددة Adamtsالتقييم لدور نشاط انزيم ١٣ [Added title page title]
- Issued also as CD
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.07.Ph.D.2012.Ah.E (Browse shelf(Opens below)) | Not for loan | 01010110059542000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.07.Ph.D.2012.Ah.E (Browse shelf(Opens below)) | 59542.CD | Not for loan | 01020110059542000 |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
ADAMTS13 is a protease that cleaves plasma VWF which will prevent the microthrombus formation caused by UL-VWF. The accumulation of UL-VWF can be caused by congenital or acquired deficiency of ADAMTS13 in patients with thrombotic thrombocytopenic purpura (TTP) which is characterized by thrombocytopenia, microangiopathic hemolytic anemia with schistocytes, variable neurologic and renal symptoms, and fever
Issued also as CD
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