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Synthesis of some novel quinoxaline benzenesulfonamide derivatives with expected anticancer activity with studying the synergistic effect of gamma irradiation / Mostafa Galal Eldin Elgazzar ; Supervised Fatma Abdelfattah Ragab , Mostafa Mohamed Soliman Ghorab

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mostafa Galal Eldin Elgazzar , 2012Description: 135 P. : charts , facsimiles ; 25cmOther title:
  • تشييد و تحضير بعض مشتقات الكينوكزالين الجديدة و التى تحتوى على مجموعة السلفوناميد ذات التأثير المحتمل كمضادات للسرطان و دراسة التأثير التحفيزى للتشعيع الجامى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry Summary: The present work deals with the synthesis of some new sulfaquinoxaline derivatives in which the 4-amino group was replaced by different pharmacophoric groups as thioureido, thiourethane or different hetarocycles. The key starting compound for the synthesis of the target compounds is 4 isothiocyanato-N-quinoxalin-2-yl-benzenesulfonamide from which 26 new compounds were synthesized and their elemental analysis and spectral data (IR, ₁H-NMR, ₁₃C-NMR and mass spectroscopy) were illustrated and discussed
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.M.Sc.2012.Mo.S (Browse shelf(Opens below)) Not for loan 01010110059556000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.M.Sc.2012.Mo.S (Browse shelf(Opens below)) 59556.CD Not for loan 01020110059556000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

The present work deals with the synthesis of some new sulfaquinoxaline derivatives in which the 4-amino group was replaced by different pharmacophoric groups as thioureido, thiourethane or different hetarocycles. The key starting compound for the synthesis of the target compounds is 4 isothiocyanato-N-quinoxalin-2-yl-benzenesulfonamide from which 26 new compounds were synthesized and their elemental analysis and spectral data (IR, ₁H-NMR, ₁₃C-NMR and mass spectroscopy) were illustrated and discussed

Issued also as CD

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