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Synthesis and biological activity of novel benzopyran derivatives / Samar Hashem Fahim ; Supervised Fatma Abdelfattah Ragab , Enayat Ibrahim Aly , Hanaa Abdelmonem Hashem

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Samar Hashem Fahim , 2013Description: 208 P. : photographs ; 25cmOther title:
  • تشييد و دراسة الفاعلية البيولوجية لبعض مشتقات البنزوبيران الجديدة [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry Summary: In the present work, certain semisynthetic benzopyran derivatives were synthesized from the naturally occurring furochromones khellin and visnagin. The synthesized compounds comprise four different classes namely: chalcones, flavones, 7- styrylfurochromones and furochromones. The in-vitro cytotoxic activity of 38 compounds against MCF-7, and 17 compounds against PC-3 in comparison to doxorubicin as a reference standard was tested
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2013.Sa.S (Browse shelf(Opens below)) Not for loan 01010110062093000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2013.Sa.S (Browse shelf(Opens below)) 62093.CD Not for loan 01020110062093000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

In the present work, certain semisynthetic benzopyran derivatives were synthesized from the naturally occurring furochromones khellin and visnagin. The synthesized compounds comprise four different classes namely: chalcones, flavones, 7- styrylfurochromones and furochromones. The in-vitro cytotoxic activity of 38 compounds against MCF-7, and 17 compounds against PC-3 in comparison to doxorubicin as a reference standard was tested

Issued also as CD

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