A combination of tumor - targeting salmonella and doxorubicin improves therapeutic effect in a murine solid tumor model / Alshaymaa Amin Zaki Elbahy ; Supervised Laila Mahran , Khaled AbouAisha , Seham AbouElnour
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TextLanguage: English Publication details: Cairo : Alshaymaa Amin Zaki Elbahy , 2012Description: 191 Leaves : photographs ; 30cmOnline resources: Dissertation note: Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacoology and Toxicology Summary: The lack of selectivity of therapeutic agents for tumor cells and the inability of chemotherapeutic drugs to act on poorly vascularized or avascularized areas of tumors remain one of the primary limitations of cancer therapy. Several studies combined tumor - targeting bacteria, which preferentially grow in hypoxic and anoxic cores of solid tumors, with chemotherapeutic agents
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Thesis
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.Ph.D.2012.Al.C (Browse shelf(Opens below)) | Not for loan | 01010110063647000 |
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Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacoology and Toxicology
The lack of selectivity of therapeutic agents for tumor cells and the inability of chemotherapeutic drugs to act on poorly vascularized or avascularized areas of tumors remain one of the primary limitations of cancer therapy. Several studies combined tumor - targeting bacteria, which preferentially grow in hypoxic and anoxic cores of solid tumors, with chemotherapeutic agents
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