Design and synthesis of novel beta - carbolines with pendant heteroaryl as PDE5 inhibitors and anticancer agents / Dalia Mohammed Sherif Elgamil ; Supervised Ashraf H. Abadi , Nermin Salah Ahmed
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2012.Da.D (Browse shelf(Opens below)) | Not for loan | 01010110063630000 |
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Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
Tadalafil is a Ý - carboline - based phosphodiesterases 5 (PDE5) inhibitor that has been introduced to the market for the treatment of male crectile dysfunction (MED). It sets through elevation of cyclic guanosine monophosphate (cGMP), which leads to vascular relaxation in the corpora cavernosa and penile crection during sexual stimulation
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