Synthesis of some novel pyrazolopyrimidine derivatives of biological interest / Walaa Ramadan Mahmoud ; Supervised Safinaz Elsayed Abbas , Enayat Ibrahim Ali , Fadi Mohsen Awadallah
Material type: TextLanguage: English Publication details: Cairo : Walaa Ramadan Mahmoud , 2013Description: 138 P. ; 25cmOther title:- تشييد بعض المشتقات الجديدة من البيرازولوبيريميدين ذات الإهتمام البيولوجي [Added title page title]
- Issued also as CD
Item type | Current library | Home library | Call number | Copy number | Status | Date due | Barcode | |
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Thesis | قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.08.05.Ph.D.2013.Wa.S (Browse shelf(Opens below)) | Not for loan | 01010110063203000 | |||
CD - Rom | مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.08.05.Ph.D.2013.Wa.S (Browse shelf(Opens below)) | 63203.CD | Not for loan | 01020110063203000 |
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry
Pyrazolopyrimidine derivatives received considerable interest as they are associated with a wide range of biological activities. The present investigation pointed toward the antitumor and antimicrobial activities of some 4- substituted - 1- phenyl pyrazolo [3, 4- d] pyrimidines. The new compounds were designed to incorporate several structural features including: alicyclic moieties as 4- (4- un / substituted phenyl)piperidin - 1- yl / piperazin - 1- yl VIIIa - f, six membered heterocycles as 6- o x o- 4- (4-un/substituted phenyl) -1, 6- dihydropyrimidine - 5- carbonitriles Xa - f and XIIa - f via a sulfanyl linker or hydrazinyl spacer, respectively and five membered heterocycles as 4- (4- un / substituted benzylidene) imidazol - 5 (4H) - one XIa - f through an amino linker
Issued also as CD
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