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Sweat glands in cutaneous drug reactions : A Histopathological, Histochemical and Immunohistochemical Study / Seham Ahmed Eltobshy ; Supervised Wedad Zoheir Mostafa , Magda Ibrahim Assaf , Mona Rabie Elsaid Abdelhalim

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Seham Ahmed Eltobshy , 2013Description: 163 P. : charts , facsimiles ; 25cmOther title:
  • الغدد العرقية فى التفاعلات الدوائية الجلدية : دراسة تحليلية للانسجة المريضة والكيمياء النسيجية والكيمياء النسيجية المناعية [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology Summary: Background: Although many drugs are excreted by eccrine sweat glands, data in literature are insufficient when it comes to histopathological, histochemical and immunohistochemical aspects of involvement of the eccrine sweat gland apparatus in adverse cutaneous drug reactions (ACDRs). Objective: To describe histopathological changes in the eccrine sweat gland apparatus in different types of ACDRs in both lesional and non-lesional skin, to evaluate their secretory function histochemically using PAS/PAS diastase and to study immunohistochemically the expression pattern of CD8, Immunoglobulin M (IgM) and Carcinoembryonic Antigen (CEA) in this group. The study aims to find associations between the different histopathological, histochemical and immunohistochemical patterns and the different causative drugs and drug reactions
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.10.Ph.D.2013.Se.S (Browse shelf(Opens below)) Not for loan 01010110063230000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.10.Ph.D.2013.Se.S (Browse shelf(Opens below)) 63230.CD Not for loan 01020110063230000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology

Background: Although many drugs are excreted by eccrine sweat glands, data in literature are insufficient when it comes to histopathological, histochemical and immunohistochemical aspects of involvement of the eccrine sweat gland apparatus in adverse cutaneous drug reactions (ACDRs). Objective: To describe histopathological changes in the eccrine sweat gland apparatus in different types of ACDRs in both lesional and non-lesional skin, to evaluate their secretory function histochemically using PAS/PAS diastase and to study immunohistochemically the expression pattern of CD8, Immunoglobulin M (IgM) and Carcinoembryonic Antigen (CEA) in this group. The study aims to find associations between the different histopathological, histochemical and immunohistochemical patterns and the different causative drugs and drug reactions

Issued also as CD

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