Single nucleotide polymorphism of il - 18 promoter region in patients with diabetic nephropathy / Shaimaa Saad Eldin Mohammad ; Supervised Laila Ahmed Rashed , Nermeen Mohammed Hasan , Hoda Abdelhamid Maamoun
Material type: TextLanguage: English Publication details: Cairo : Shaimaa Saad Eldin Mohammad , 2013Description: 108 P. : facsimiles ; 25cmOther title:- التحور الجينى للإنترلوكين - 18 فى مرضى الاعتلال الكلوى السكرى [Added title page title]
- Issued also as CD
Item type | Current library | Home library | Call number | Copy number | Status | Date due | Barcode | |
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Thesis | قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.03.M.Sc.2013.Sh.S (Browse shelf(Opens below)) | Not for loan | 01010110063500000 | |||
CD - Rom | مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.03.M.Sc.2013.Sh.S (Browse shelf(Opens below)) | 63500.CD | Not for loan | 01020110063500000 |
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Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
Between 20% and 40% of patients with diabetes ultimately develop diabetic nephropathy (DN), which is the most common cause of end stage renal disease requiring dialysis. Interleukin - 18 (IL - 18) is a pro - inflammatory cytokine and possibly plays an important role in the pathogenesis of diabetic nephropathy. The promoter region of the human IL - 18 gene has common single nucleotide polymorphisms at positions - 607 and - 137. These polymorphisms have been shown to regulate the IL - 18 production of peripheral blood monocytes and be associated with the transcriptional activity of the IL - 18 gene
Issued also as CD
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