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Micronucleus assay as biomarker for chromosome malsegregation in young mothers with down syndrome children / Mohamed Badie Taher Kattaria ; Supervised Sawsan Abdelhady Hassan , Hanan Hosny Afifi , Eman Abdelghany Abdelghany

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohamed Badie Taher Kattaria , 2014Description: 120 P. : charts , facsimiles ; 25cmOther title:
  • فحص النوييات فى الأمهات الشابات للأطفال المصابين بمتلازمة داون كدلاله بيولوجية لعيوب فصل الكروموسومات [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: We observed an increased frequency of binucleated micronucleated lymphocytes in mothers who had a down syndrome (DS) child before 30 years of age and the fluorescence in situ hybridization analysis revealed that micronuclei were mainly originating from malsegregation chromosome 21. The present study included 62 Egyptian young mothers (age < 30 y) ,free from any chronic disease, not taking any regular drugs, there were divided into 2 groups: Group 1; 22 mothers of classic down syndrome children and Group 2; 40 healthy Egyptian matched females as control group
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Mo.M (Browse shelf(Opens below)) Not for loan 01010110063725000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Mo.M (Browse shelf(Opens below)) 63725.CD Not for loan 01020110063725000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

We observed an increased frequency of binucleated micronucleated lymphocytes in mothers who had a down syndrome (DS) child before 30 years of age and the fluorescence in situ hybridization analysis revealed that micronuclei were mainly originating from malsegregation chromosome 21. The present study included 62 Egyptian young mothers (age < 30 y) ,free from any chronic disease, not taking any regular drugs, there were divided into 2 groups: Group 1; 22 mothers of classic down syndrome children and Group 2; 40 healthy Egyptian matched females as control group

Issued also as CD

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