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Formulation and evaluation of controlled release parenteral in situ forming drug delivery system / Mary Yosry Aziz Faragallah ; Supervised Soad A. Yehia , Sally A. Abdelhalim

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mary Yosry Aziz Faragallah , 2014Description: 175 P. : charts , facsimiles ; 25cmOther title:
  • ص{u٠٦أأ}اغة و تق{u٠٦أأ}{u٠٦أأ}م أنظمة توص{u٠٦أأ}ل منضبطة الانطلاق متكونة فى الموضع عن طر{u٠٦أأ}ق الحقن [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics Summary: The aim of this thesis is to formulate controlled release in situ forming implants (ISI) and in situ forming microparticles (ISM) containing lornoxicam for management of postoperative and arthritic pain in order to decrease dosing frequency and increase patient compliance. Polymeric in situ implant solutions were prepared using different concentrations of Poly - DL - lactide (PDL) or DL - lactide/glycolide copolymer (PDLG) solutions with different inherent viscosities in N{u2013} methyl pyrrolidone (NMP) using 2² X 4 factorial experimental design, where sixteen formulae were prepared. Non polymeric in situ implant solutions prepared using different concentrations of lipids like cetyl alcohol and stearyl alcohol and also sucrose acetate isobutyrate (SAIB) using 3² factorial experimental design, resulting in nine formulae
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2014.Ma.F (Browse shelf(Opens below)) Not for loan 01010110063896000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2014.Ma.F (Browse shelf(Opens below)) 63896.CD Not for loan 01020110063896000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

The aim of this thesis is to formulate controlled release in situ forming implants (ISI) and in situ forming microparticles (ISM) containing lornoxicam for management of postoperative and arthritic pain in order to decrease dosing frequency and increase patient compliance. Polymeric in situ implant solutions were prepared using different concentrations of Poly - DL - lactide (PDL) or DL - lactide/glycolide copolymer (PDLG) solutions with different inherent viscosities in N{u2013} methyl pyrrolidone (NMP) using 2² X 4 factorial experimental design, where sixteen formulae were prepared. Non polymeric in situ implant solutions prepared using different concentrations of lipids like cetyl alcohol and stearyl alcohol and also sucrose acetate isobutyrate (SAIB) using 3² factorial experimental design, resulting in nine formulae

Issued also as CD

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