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Overexpression of her- 2 neu in papillary thyroid carcinoma : Histopathological and immunohistochemical study / Mohamed Emam Mohamed Sedqi ; Supervised Ahmed Mahmoud Abdelaziz , Samia Mohamed Gabal , Dina Omar Helmy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohamed Emam Mohamed Sedqi , 2013Description: 103 P. : facsimiles ; 25cmOther title:
  • التعبير عن بروتين الهير-٢ نيو فى سرطان الغدة الدرقية الحليمى : دراسة هيستوباثولوجية و مناعية كيميائية [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology Summary: Papillary thyroid carcinoma is the most common type of well differentiated thyroid carcinoma and it accounts for at least 70% of all follicular - cell derived thyroid malignancies. Conflicting data exist about the prevalence of HER- 2 / neu overexpression in papillary thyroid carcinoma ranging from 6.9 to 70 %. In the current study we tried to clarify the extent of expression and its relationship to clinicopathological parameters. This study involved 50 cases of papillary thyroid carcinoma diagnosed in thyroidectomy specimens. HER- 2 / neu immunohistochemistry was performed using the C- erbB- 2 gene product. Out of 50 specimens, 28 were HER- 2 / neu positive (56%) and 22 (44%) were HER- 2 / neu negative. No significant relationship was found between membranous HER- 2 expression and any of the clinicopathological parameters
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.27.M.Sc.2013.Mo.O (Browse shelf(Opens below)) Not for loan 01010110063902000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.27.M.Sc.2013.Mo.O (Browse shelf(Opens below)) 63902.CD Not for loan 01020110063902000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology

Papillary thyroid carcinoma is the most common type of well differentiated thyroid carcinoma and it accounts for at least 70% of all follicular - cell derived thyroid malignancies. Conflicting data exist about the prevalence of HER- 2 / neu overexpression in papillary thyroid carcinoma ranging from 6.9 to 70 %. In the current study we tried to clarify the extent of expression and its relationship to clinicopathological parameters. This study involved 50 cases of papillary thyroid carcinoma diagnosed in thyroidectomy specimens. HER- 2 / neu immunohistochemistry was performed using the C- erbB- 2 gene product. Out of 50 specimens, 28 were HER- 2 / neu positive (56%) and 22 (44%) were HER- 2 / neu negative. No significant relationship was found between membranous HER- 2 expression and any of the clinicopathological parameters

Issued also as CD

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