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Association of miR - 146a gene polymorphism and ovarian cancer susceptibility / Ahmed Samir Seddik Elshazly ; Supervised Marianne Samir Makboul Issac , Amal Fawzy Mohammed , Heba Allah Gamal Eldin Mohammed Mahmoud

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Samir Seddik Elshazly , 2014Description: 115 P. : charts ; 25cmOther title:
  • ١٤٦و الإصابة بمرض سرطان المبيض a العلاقة بين الأشكال الجينية المتعددة لحمض الريبونيوكلييك الصغير [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Ovarian cancer is the third most common cancer of the female genital tract and the leading cause of cancer death associated with gynecologic tumors. MicroRNAs regulate at least 60% of human genes, including tumor suppressor genes and oncogenes and, thereby, can affect cancer risk. This study aims to investigate the potential association between miR - 146a (rs2910164) polymorphism and ovarian cancer risk in a group of Egyptian patients and whether there is an association between this polymorphism and some clinico-pathological parameters in the patients. Fifty newly diagnosed ovarian cancer cases, fifteen benign ovarian cases and 35 healthy control females were recruited in this study. MiR - 146a (rs2910164) polymorphism was detected by TaqMan - Real time PCR assay
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.M.Sc.2014.Ah.A (Browse shelf(Opens below)) Not for loan 01010110064128000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.M.Sc.2014.Ah.A (Browse shelf(Opens below)) 64128.CD Not for loan 01020110064128000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Ovarian cancer is the third most common cancer of the female genital tract and the leading cause of cancer death associated with gynecologic tumors. MicroRNAs regulate at least 60% of human genes, including tumor suppressor genes and oncogenes and, thereby, can affect cancer risk. This study aims to investigate the potential association between miR - 146a (rs2910164) polymorphism and ovarian cancer risk in a group of Egyptian patients and whether there is an association between this polymorphism and some clinico-pathological parameters in the patients. Fifty newly diagnosed ovarian cancer cases, fifteen benign ovarian cases and 35 healthy control females were recruited in this study. MiR - 146a (rs2910164) polymorphism was detected by TaqMan - Real time PCR assay

Issued also as CD

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