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Detection of complications following intravenous immunoglobulin infusion in children / Shrouk Moataz Sayed Abdallah ; Supervised Aisha Mahmoud Elmarsafy , Ilham Youssry Ibrahim , Nermeen Mouftah Galal

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Shrouk Moataz Sayed Abdallah , 2013Description: 117 P. : facsimiles ; 25cmOther title:
  • رصد المضاعفات الناتجة عن العلاج الوريدي بالأجسام المناعية المضادة في الأطفال [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Background: Intravenous immunoglobulins (IVIGs) are scarce biological products used in a broad variety of disorders. Tolerance to infusions is usually good but adverse events, including some serious ones, have been reported. Aim of the work: The study aimed for detection of adverse events that occur during and following intravenous immunoglobulin (IVIG) infusion; in relation to preparation, dosing regimen, duration and infusion hours, with identification of patients at risk of developing these adverse events. Patients and methods: To detect the complications of IVIG infusions, an observational study was implemented on a cohort of 55 patients (birth to18 years) who received 62 infusion sessions for different disease conditions over a period of 6 months, 2013. Clinical evaluation and laboratory assessment were done with follow up 7-10 days afterwards. Results: Adverse events occurred following 37.1% of IVIG infusions ranging from common mild rate related reactions such as skin rash, fever and chills to more severe anaphylactoid ones as serum sickness (3.2%) and rare ones such as significant anemia (22.6%) and acute renal failure (3.2%). Infusion rate and the presence of risk factors are strong predicting variable for numerous reactions
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2013.Sh.D (Browse shelf(Opens below)) Not for loan 01010110064061000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2013.Sh.D (Browse shelf(Opens below)) 64061.CD Not for loan 01020110064061000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Intravenous immunoglobulins (IVIGs) are scarce biological products used in a broad variety of disorders. Tolerance to infusions is usually good but adverse events, including some serious ones, have been reported. Aim of the work: The study aimed for detection of adverse events that occur during and following intravenous immunoglobulin (IVIG) infusion; in relation to preparation, dosing regimen, duration and infusion hours, with identification of patients at risk of developing these adverse events. Patients and methods: To detect the complications of IVIG infusions, an observational study was implemented on a cohort of 55 patients (birth to18 years) who received 62 infusion sessions for different disease conditions over a period of 6 months, 2013. Clinical evaluation and laboratory assessment were done with follow up 7-10 days afterwards. Results: Adverse events occurred following 37.1% of IVIG infusions ranging from common mild rate related reactions such as skin rash, fever and chills to more severe anaphylactoid ones as serum sickness (3.2%) and rare ones such as significant anemia (22.6%) and acute renal failure (3.2%). Infusion rate and the presence of risk factors are strong predicting variable for numerous reactions

Issued also as CD

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