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The role of pon -1 activity and polymorphism of pon -1 and cytochrome P450 genes in suseptability assessment to organophosphorus poisoning in Egyptian cases / Amr Mohamed Tawfik Khattab ; Supervised Aly Gamal Eldin Abdelaal , Alaa Abdelhamid Mekdad , Abeer Ahmed Zayed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Amr Mohamed Tawfik Khattab , 2014Description: 135 P. : charts , facsimiles ; 25cmOther title:
  • دور نشاط إنزيم البارا أوكسونيز و تعدد الأشكال الجينيه لانزيم البارا أوكسونيز و ستكروم 450 فى تقييم قابلية التسمم بمبيدات الفسفور العضويه فى حالات مصرية [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Forensic Medicine-Toxicology Summary: Organophosphorus insecticides result in a huge number of intoxications because of the widespread use and the easy accessibility. Metabolism of organophosphorus compounds depends on a diversity of enzymes; the most important of which are paraoxonase and cytochrome P450. The present study aims to identify a possible association between the paraoxonase enzyme activity and the susceptibility for organophosphorus poisoning in both acute and chronic forms. Genetic polymorphism of PON1 192 and CYP - 2D6 genes are studied to investigate individual susceptibility to organophosphorus poisoning
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.13.Ph.D.2014.Am.R (Browse shelf(Opens below)) Not for loan 01010110064262000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.13.Ph.D.2014.Am.R (Browse shelf(Opens below)) 64262.CD Not for loan 01020110064262000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Forensic Medicine-Toxicology

Organophosphorus insecticides result in a huge number of intoxications because of the widespread use and the easy accessibility. Metabolism of organophosphorus compounds depends on a diversity of enzymes; the most important of which are paraoxonase and cytochrome P450. The present study aims to identify a possible association between the paraoxonase enzyme activity and the susceptibility for organophosphorus poisoning in both acute and chronic forms. Genetic polymorphism of PON1 192 and CYP - 2D6 genes are studied to investigate individual susceptibility to organophosphorus poisoning

Issued also as CD

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