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Study of the potential effects of certain natural products on elevated intra - ocular pressure induced experimentally in Animals / Lobna Ahmed Taher Ahmed Abdelwahab ; Supervised Aiman S. Elkhatib , Amany I. Elbrairy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Lobna Ahmed Taher Ahmed Abdelwahab , 2014Description: 151 P. : charts ; 25cmOther title:
  • دراسة التأث{u٠٦أأ}ر المحتمل لمنتجات طب{u٠٦أأ}ع{u٠٦أأ}ة مع{u٠٦أأ}نة فى ارتفاع ضغط الع{u٠٦أأ}ن المحدث تجر{u٠٦أأ}ب{u٠٦أأ}ا فى الح{u٠٦أأ}وانات [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology Summary: Ginkgo biloba and green tea have attracted interest due to their neuroprotective, potent antioxidant, and blood flow regulatory activities. The current study aimed to assess the potential effects of standardized extracts of ginkgo biloba (EGb 761) and green tea on ocular hypertension induced in rabbits by a single subconjunctival administration of betamethasone (3.5mg). The latter produced a sustainable increase in intraocular pressure (IOP), measured by tonometry, starting from day 7 post administration. After ocular hypertension has been established namely, day 7, animals were randomly allocated into 7 groups where group I was left untreated, groups II and III were topically treated with timolol (0.5 %) and EGb 761 (0.05 %), respectively, groups IV and V received orally EGb 761 (20mg / kg) and green tea (300 mg / kg), respectively, groups VI and VII received combination of either oral EGb 761 (20mg / kg) or green tea (300mg / kg) plus topical timolol (0.5 %), respectively. All the mentioned treatments were given once daily for 7 days
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.09.M.Sc.2014.Lo.S (Browse shelf(Opens below)) Not for loan 01010110064299000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.09.M.Sc.2014.Lo.S (Browse shelf(Opens below)) 64299.CD Not for loan 01020110064299000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

Ginkgo biloba and green tea have attracted interest due to their neuroprotective, potent antioxidant, and blood flow regulatory activities. The current study aimed to assess the potential effects of standardized extracts of ginkgo biloba (EGb 761) and green tea on ocular hypertension induced in rabbits by a single subconjunctival administration of betamethasone (3.5mg). The latter produced a sustainable increase in intraocular pressure (IOP), measured by tonometry, starting from day 7 post administration. After ocular hypertension has been established namely, day 7, animals were randomly allocated into 7 groups where group I was left untreated, groups II and III were topically treated with timolol (0.5 %) and EGb 761 (0.05 %), respectively, groups IV and V received orally EGb 761 (20mg / kg) and green tea (300 mg / kg), respectively, groups VI and VII received combination of either oral EGb 761 (20mg / kg) or green tea (300mg / kg) plus topical timolol (0.5 %), respectively. All the mentioned treatments were given once daily for 7 days

Issued also as CD

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