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Relationship between matrix metalloproteinase 10 (MMP-10) and atherosclerosis in patients with chronic kidney disease / Mohammed Mustafa Mohammed ; Supervised Dawlat Belal , Manal Eldeeb , Khalid Kaffas

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohammed Mustafa Mohammed , 2014Description: 184 P. : charts , facsimiles ; 25cmOther title:
  • العلاقة بين مستوى ماتريكس ميتالوبروتيناز- ١٠ و تصلب الشرايين فى مرضى القصر الكلوى المزمن [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine Summary: Cardiovascular diseases (CVD) are the leading cause of death in patients with chronic kidney disease (CKD). As matrix metalloproteinases have a major role in atherosclerosis, we investigated the relationship between MMP 10 and severity of atherosclerosis in patients with chronic kidney disease. This was evaluated in a cross sectional, observational study of 30 patients with different stages of kidney disease, 30 patients on dialysis and 20 controls. The severity of atherosclerosis was estimated with carotid intima media thickness (CIMT) by carotid ultrasound. Serum levels of the matrix metalloproteinase 10 (MMP 10) was measured by ELISA and were significantly increased in patients with kidney disease compared with the healthy controls, and higher in patients on dialysis than in earlier stages of CKD
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.Ph.D.2014.Mo.R (Browse shelf(Opens below)) Not for loan 01010110064602000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.Ph.D.2014.Mo.R (Browse shelf(Opens below)) 64602.CD Not for loan 01020110064602000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

Cardiovascular diseases (CVD) are the leading cause of death in patients with chronic kidney disease (CKD). As matrix metalloproteinases have a major role in atherosclerosis, we investigated the relationship between MMP 10 and severity of atherosclerosis in patients with chronic kidney disease. This was evaluated in a cross sectional, observational study of 30 patients with different stages of kidney disease, 30 patients on dialysis and 20 controls. The severity of atherosclerosis was estimated with carotid intima media thickness (CIMT) by carotid ultrasound. Serum levels of the matrix metalloproteinase 10 (MMP 10) was measured by ELISA and were significantly increased in patients with kidney disease compared with the healthy controls, and higher in patients on dialysis than in earlier stages of CKD

Issued also as CD

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