Effect of induced hypercholesterolemia on the testis and epididymis of adult albino rat and the possible protective role of atorvastatin and selenium : Histological and ultrastructural study / Reda Abdelnasser Emam ; Supervised Fayza Abdelraouf Abdelgawad , Ehab Abdelaziz Ahmed , Ayman Aboelenien Rizk

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Reda Abdelnasser Emam

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TextLanguage: English Publication details: Cairo : Reda Abdelnasser Emam , 2014Description: 178 P. : charts , facsimiles ; 25cmOther title:

تأثير الزيادة المستحثة للكوليستيرول فى الدم على الخصية و البربخ للجر{uئإءآ} الأبيض البالغ و الدور الوقائى المحتمل للأتور{u٠٦ء٤}استاتن و السيلينيوم : دراسة هستولوجية و فائقة الدقة [Added title page title]

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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anatomy Summary: There is a close association between ischemic cardiovascular disease and hypercholesterolemia. The present study was aimed to evaluate the effect of induced hypercholesterolemia on the testis and epididymis of adult albino rats and to elucidate the possible protective role of atorvastatin and selenium. Fifty adult albino Wistar rats were divided into five groups; control group, sham control, induced hypercholesterolemia group, induced hypercholesterolemia treated with atorvastatin group and induced hypercholesterolemia treated with selenium. The effects were monitored histologicaly, ultrastructurally, Biochemically and morphometrically. Induced hypercholesterolemia produced marked histological and ultrastructural changes in the testis. Morphometrically, there was a significant decrease (p < 0.0001) in the diameter of the seminiferous tubules, significant increase (p < 0.0001) in the collagen fibers in the testes of rats and significant reduction (p < 0.0001) in the polysaccharides content of induced hypercholesterolemia group rats as compared to the control groups

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Item type	Current library	Home library	Call number	Copy number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.02.Ph.D.2014.Re.E (Browse shelf(Opens below))		Not for loan	01010110064725000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.02.Ph.D.2014.Re.E (Browse shelf(Opens below))	64725.CD	Not for loan	01020110064725000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anatomy

There is a close association between ischemic cardiovascular disease and hypercholesterolemia. The present study was aimed to evaluate the effect of induced hypercholesterolemia on the testis and epididymis of adult albino rats and to elucidate the possible protective role of atorvastatin and selenium. Fifty adult albino Wistar rats were divided into five groups; control group, sham control, induced hypercholesterolemia group, induced hypercholesterolemia treated with atorvastatin group and induced hypercholesterolemia treated with selenium. The effects were monitored histologicaly, ultrastructurally, Biochemically and morphometrically. Induced hypercholesterolemia produced marked histological and ultrastructural changes in the testis. Morphometrically, there was a significant decrease (p < 0.0001) in the diameter of the seminiferous tubules, significant increase (p < 0.0001) in the collagen fibers in the testes of rats and significant reduction (p < 0.0001) in the polysaccharides content of induced hypercholesterolemia group rats as compared to the control groups

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