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Study of serum hepcidin as a diagnostic tool of iron overload in Egyptian children with beta - thalassemia major and intermedia / Reham Ragab Elsaid Mohamed ; Supervised Ahmed Maher Kaddah , Amina Abdelsalam Mahmoud , Marwa Salah Farhan

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Reham Ragab Elsaid Mohamed , 2014Description: 101 P. : charts ; 25cmOther title:
  • دراسة السيروم هيبسيدين كأداة تشخيصية للتحميل المفرط للحديد فى الاطفال المصريين المصابين بأنيميا البحر المتوسط [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Iron homeostasis proved to be regulated by hepatic peptide hormone "Hepcidin". Iron homeostasis is disturbed in beta - thalassemia and results in iron overload with or without transfusion dependence. To investigate serum hepcidin level and its potential usefulness in the diagnosis of iron overload in children with beta thalassemia major and intermedia as well as to assess the relationship between hepcidin level and various clinical and laboratory characteristics of recruited patients. A prospective study conducted at the Hematology clinic, elmonira children's Hospital, Cairo University. Thirty thalassemia intermedia (TI group), 30 thalassemia major (TM group) and 60 healthy - age and sex- matched subjects were enrolled. All patients were subjected to history taking and complete physical examination. Complete blood count, liver function tests, serum bilirubin (total, direct), serum ferritin and serum hepcidin level was measured by human hepcidin, ELISA Kit
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Re.S (Browse shelf(Opens below)) Not for loan 01010110064929000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Re.S (Browse shelf(Opens below)) 64929.CD Not for loan 01020110064929000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Iron homeostasis proved to be regulated by hepatic peptide hormone "Hepcidin". Iron homeostasis is disturbed in beta - thalassemia and results in iron overload with or without transfusion dependence. To investigate serum hepcidin level and its potential usefulness in the diagnosis of iron overload in children with beta thalassemia major and intermedia as well as to assess the relationship between hepcidin level and various clinical and laboratory characteristics of recruited patients. A prospective study conducted at the Hematology clinic, elmonira children's Hospital, Cairo University. Thirty thalassemia intermedia (TI group), 30 thalassemia major (TM group) and 60 healthy - age and sex- matched subjects were enrolled. All patients were subjected to history taking and complete physical examination. Complete blood count, liver function tests, serum bilirubin (total, direct), serum ferritin and serum hepcidin level was measured by human hepcidin, ELISA Kit

Issued also as CD

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