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Early versus late indomethacin treatment for patent ductus arteriosus in premature infants / Hussein Nabil Abdallah ; Supervised Mohamed Fawzan Shaltout , Mohamed Ahmed Aboulhassan , Alaa Eldin Adel Sobeih

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Hussein Nabil Abdallah , 2014Description: 98 P. : charts , facsimiles ; 25cmOther title:
  • المقارنة بين الاستخدام المبكر والمتأخر لعقار الاندوميثاسين لغلق القناة الشريانية فى الأطفال المبتسرين [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Patent ductus arteriosus is a postnatal communication, usually between the main pulmonary trunk and the descending thoracic aorta. The clinical consequences of PDA are related to the magnitude of the left-to-right shunt through the PDA with its associated change in blood flow to the lung, kidneys, and intestine, leading to tachypnea, apnea, CO2 retention and increased need to mechanical ventilation. Indomethacin is the only non-selective cyclooxygenase inhibitor approved by FDA for the treatment of PDA. It has been clearly established both by observational studies and randomized trials that indomethacin increases the rate of PDA closure within 24 hours of its administration. Less clearly established are the optimal timing, dose, and duration of treatment
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Hu.E (Browse shelf(Opens below)) Not for loan 01010110065277000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Hu.E (Browse shelf(Opens below)) 65277.CD Not for loan 01020110065277000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Patent ductus arteriosus is a postnatal communication, usually between the main pulmonary trunk and the descending thoracic aorta. The clinical consequences of PDA are related to the magnitude of the left-to-right shunt through the PDA with its associated change in blood flow to the lung, kidneys, and intestine, leading to tachypnea, apnea, CO2 retention and increased need to mechanical ventilation. Indomethacin is the only non-selective cyclooxygenase inhibitor approved by FDA for the treatment of PDA. It has been clearly established both by observational studies and randomized trials that indomethacin increases the rate of PDA closure within 24 hours of its administration. Less clearly established are the optimal timing, dose, and duration of treatment

Issued also as CD

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