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Screening for cardiovascular malformations and complications in turner syndrome / Mohamed Samir Eid Abdelwahab ; Supervised Mona Atteya Mahmoud Hana , Mohamed Mohamed Ismail Elkanishy , Rania Zakaria Hassen AbuElezz

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohamed Samir Eid Abdelwahab , 2014Description: 102 Leaves : facsimiles , photographs ; 30cmOther title:
  • الكشف عن عيوب و مضاعفات القلب و الأوعية الـدموية فى مـتلازمة تيرنر [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Turner syndrome (TS) is caused by complete or partial monosomy of the X chromosome and has an overall prevalence of approximately 1 in 2500 live births of girls. It is characterized phenotypically by short stature and gonadal dysgenesis. The prevalence of cardiovascular abnormalities among patients with Turner syndrome varies in different series between 20% and 40%. It is higher in patients with monosomy X than in those with structural abnormalities of the X chromosome, and also higher in girls with a more pronounced clinical phenotype. Cardiovascular anomalies include aortic dilatation which may contribute to increased risk of aortic dissection. Thus, periodic cardiac magnetic resonance (CMR) imaging screening of persons with turner syndrome is beneficial. Although echocardiography was considered the mainstay of diagnosis, CMR can detect dilatation missed on echocardiography. Cardiac imaging, preferably magnetic resonance imaging, should be performed at diagnosis and repeated at 3 to 5 yr intervals to assess for congenital heart abnormalities and the emergence of aortic dilatation, a precursor to aortic dissection. Hypertension is a risk factor that should be aggressively treated
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Mo.S (Browse shelf(Opens below)) Not for loan 01010110065506000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Mo.S (Browse shelf(Opens below)) 65506.CD Not for loan 01020110065506000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Turner syndrome (TS) is caused by complete or partial monosomy of the X chromosome and has an overall prevalence of approximately 1 in 2500 live births of girls. It is characterized phenotypically by short stature and gonadal dysgenesis. The prevalence of cardiovascular abnormalities among patients with Turner syndrome varies in different series between 20% and 40%. It is higher in patients with monosomy X than in those with structural abnormalities of the X chromosome, and also higher in girls with a more pronounced clinical phenotype. Cardiovascular anomalies include aortic dilatation which may contribute to increased risk of aortic dissection. Thus, periodic cardiac magnetic resonance (CMR) imaging screening of persons with turner syndrome is beneficial. Although echocardiography was considered the mainstay of diagnosis, CMR can detect dilatation missed on echocardiography. Cardiac imaging, preferably magnetic resonance imaging, should be performed at diagnosis and repeated at 3 to 5 yr intervals to assess for congenital heart abnormalities and the emergence of aortic dilatation, a precursor to aortic dissection. Hypertension is a risk factor that should be aggressively treated

Issued also as CD

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