Functional changes in the intestinal tract caused by radiation induced mucositis in rats / Rania Mostafa Elhazek ; Supervised Mohamed T. Khayyal , Mona A. Elghazaly

By:

Rania Mostafa Elhazek

Contributor(s):

Material type: Text

TextLanguage: English Publication details: Cairo : Rania Mostafa Elhazek , 2014Description: 80 P. : charts , facsimiles ; 25cmOther title:

التغيرات الوظيفية في الامعاء الناتجة من التهاب الغشاء المخاطي المحدث بالاشعاع في الجرذان [Added title page title]

Subject(s):

Available additional physical forms:

Issued also as CD

Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy- Department of Pharmacology and Toxicology Summary: Irradiation of tissues during the course of therapeutic radiation can result in a range of side effects. Arguably the small intestine is the organ of the gastrointestinal mucosa that is most susceptible to damage during a course of radiotherapy. We investigated the effect of ionizing radiation on the integrity and functions of the small intestine. Some natural agents such as; STW 5 (marketed as Iberogast, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany) and aqueous propolis extract (Propharma, Havdrup, Denmark), were tested for their efficacy in protection against intestinal mucositis induced in irradiated rats. Materials and methods: Intestinal mucositis was induced in rats by irradiation at different acute levels of 4, 6 and 8Gy. STW 5 (2.5, 5 and 10 ml/kg) or aqueous propolis extract (450, 650 and 850 mg/kg) were delivered orally for 5 days before irradiation and 2 days after. Rats were sacrificed, jejunum segments were exposed to semi-quantitative histological examination to determine the overall damage severity (ODS) score

Tags from this library: No tags from this library for this title. Log in to add tags.

Average rating: 0.0 (0 votes)

Holdings
Item type	Current library	Home library	Call number	Copy number	Status	Date due	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.08.09.Ph.D.2014.Ra.F (Browse shelf(Opens below))		Not for loan		01010110065818000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.08.09.Ph.D.2014.Ra.F (Browse shelf(Opens below))	65818.CD	Not for loan		01020110065818000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy- Department of Pharmacology and Toxicology

Irradiation of tissues during the course of therapeutic radiation can result in a range of side effects. Arguably the small intestine is the organ of the gastrointestinal mucosa that is most susceptible to damage during a course of radiotherapy. We investigated the effect of ionizing radiation on the integrity and functions of the small intestine. Some natural agents such as; STW 5 (marketed as Iberogast, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany) and aqueous propolis extract (Propharma, Havdrup, Denmark), were tested for their efficacy in protection against intestinal mucositis induced in irradiated rats. Materials and methods: Intestinal mucositis was induced in rats by irradiation at different acute levels of 4, 6 and 8Gy. STW 5 (2.5, 5 and 10 ml/kg) or aqueous propolis extract (450, 650 and 850 mg/kg) were delivered orally for 5 days before irradiation and 2 days after. Rats were sacrificed, jejunum segments were exposed to semi-quantitative histological examination to determine the overall damage severity (ODS) score

Issued also as CD

There are no comments on this title.

to post a comment.