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Comparative study between morphine and dexmedetomidine for postoperative analgesia in patients undergoing cancer surgeries / Noha Mohamed Abdel Moneim Mohamed ; Supervised Mohga Adel Samy , Wael Ahmed Ebrahim , Nermin Safwat Boules

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Noha Mohamed Abdelmoneim Mohamed , 2015Description: 74 P. : charts ; 25cmOther title:
  • دراسة مقارنة بين عقار المورفين وعقار الديكسميديتوميدين فى تسكين الام ما بعد عمليات الاورام [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Anesthesia and Pain Relief Summary: Comparative study between morphine and dexmedetomidine for postoperative analgesia in patients undergoing cancer surgeries.The aim of the study is to compare the postoperative pain-relieving quality and effect on stress response of a continuous infusion of dexmedetomidine (low & high doses) with I.V morphine infusion in patients undergoing cancer surgeries. In conclusion,morphine has better postoperative analgesia than dexmedetomidine (low and high dose) during the first 40 hours postoperatively apart from 16 and 20 hours postoperatively; there is no difference in analgesia between the two drugs. Dexmedetomidine (low and high dose) provides analgesia, sedation and alleviates stress response in the form of lowering blood glucose and serum cortisol. However low dexmedetomidine is better than high dose dexmedetomidine as it has less adverse effects. Further and larger studies are needed to assess the optimum regimen of dexmedetomidine for postoperative analgesia
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.01.Ph.D.2015.No.C (Browse shelf(Opens below)) Not for loan 01010110066410000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.01.Ph.D.2015.No.C (Browse shelf(Opens below)) 66410.CD Not for loan 01020110066410000

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Anesthesia and Pain Relief

Comparative study between morphine and dexmedetomidine for postoperative analgesia in patients undergoing cancer surgeries.The aim of the study is to compare the postoperative pain-relieving quality and effect on stress response of a continuous infusion of dexmedetomidine (low & high doses) with I.V morphine infusion in patients undergoing cancer surgeries. In conclusion,morphine has better postoperative analgesia than dexmedetomidine (low and high dose) during the first 40 hours postoperatively apart from 16 and 20 hours postoperatively; there is no difference in analgesia between the two drugs. Dexmedetomidine (low and high dose) provides analgesia, sedation and alleviates stress response in the form of lowering blood glucose and serum cortisol. However low dexmedetomidine is better than high dose dexmedetomidine as it has less adverse effects. Further and larger studies are needed to assess the optimum regimen of dexmedetomidine for postoperative analgesia

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