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ReckGene promoter rs10814325 polymorphism in Egyptian patients with hepatocellular carcinoma on top of chronic hepatitis C viral infection / Amal Bahgat Fakhry ; Supervised Dalia Ibrahim Ramadand , Asmaa Ismail Ahmed , Mahmoud Abdo Abdelalim

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Amal Bahgat Fakhry , 2015Description: 146 P. : charts , facsimiles ; 25cmOther title:
  • في المرضي المصريين المصابين بسرطان الكبد الناتج عن اللالتهاب الكبدى الفيروسي سيrs 10814325المحفز RECKالتعدد الشكلى للجين [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Background: Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the third leading cause of cancer-related death worldwide. The reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) gene is a novel transformation suppressor gene against ras oncogenes. It encodes a membrane-anchored glycoprotein that can negatively regulate matrix metalloproteinases (MMPs) and inhibit tumor invasion, angiogenesis and metastasis. Aim of the work: The aim of this study was to analyze the association between RECK gene rs10814325 single-nucleotide polymorphism (SNP) and HCC susceptibility and its association with various clinic- pathological and laboratory data of the patients.
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.M.Sc.2015.Am.R (Browse shelf(Opens below)) Not for loan 01010110066492000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.M.Sc.2015.Am.R (Browse shelf(Opens below)) 66492.CD Not for loan 01020110066492000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Background: Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the third leading cause of cancer-related death worldwide. The reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) gene is a novel transformation suppressor gene against ras oncogenes. It encodes a membrane-anchored glycoprotein that can negatively regulate matrix metalloproteinases (MMPs) and inhibit tumor invasion, angiogenesis and metastasis. Aim of the work: The aim of this study was to analyze the association between RECK gene rs10814325 single-nucleotide polymorphism (SNP) and HCC susceptibility and its association with various clinic- pathological and laboratory data of the patients.

Issued also as CD

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