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Design. synthesis and biological activities of novel benzopyrones / Akram Hifny Abdelhaleem ; Supervised Sohair L. Elansary , Doaa E. Abdelrahman

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Akram Hifny Abdelhaleem , 2015Description: 171 P. : charts ; 25cmOther title:
  • تصميم وتشييد ودراسة النشاط البيولوجى لبعض البتروبيرونات [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry Summary: Benzopyrones and furobenzopyrones are significant class of natural compounds isolated mainly from higher plants associated to the families of Rutaceae. They have a broad range and diversity of biological activities such as antibacterial, antihistaminic, vasorelaxant and bronchodilation activities. Cardiovascular diseases [coronary heart diseases, hypertension and peripheral artery diseases] are by far the main causes of the world wide mortality. Vasorelaxants, vascular smooth muscle agents, are considered one of the most important classes for management of hypertension. Bronchial asthma is considered one of the most common chronic diseases worldwide. Airway hyper-responsiveness to histamine is a hallmark of asthma, and histamine inhalation reproduces asthma symptoms. The H1 receptor antagonists have been proved to play an important role for a number of clinical indications including allergic conditions, chronic idiopathic urticaria, motion sickness, vertigo, insomnia and asthma.
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2015.Ak.D (Browse shelf(Opens below)) Not for loan 01010110066517000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2015.Ak.D (Browse shelf(Opens below)) 66517.CD Not for loan 01020110066517000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

Benzopyrones and furobenzopyrones are significant class of natural compounds isolated mainly from higher plants associated to the families of Rutaceae. They have a broad range and diversity of biological activities such as antibacterial, antihistaminic, vasorelaxant and bronchodilation activities. Cardiovascular diseases [coronary heart diseases, hypertension and peripheral artery diseases] are by far the main causes of the world wide mortality. Vasorelaxants, vascular smooth muscle agents, are considered one of the most important classes for management of hypertension. Bronchial asthma is considered one of the most common chronic diseases worldwide. Airway hyper-responsiveness to histamine is a hallmark of asthma, and histamine inhalation reproduces asthma symptoms. The H1 receptor antagonists have been proved to play an important role for a number of clinical indications including allergic conditions, chronic idiopathic urticaria, motion sickness, vertigo, insomnia and asthma.

Issued also as CD

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